Global Orthopedic Joint Reconstruction Market By Product (Demineralized Bone Matrix (DBM), Allograft, Bone Morphogenetic
Protein (BMP), Viscosupplementation Products, Synthetic Bone Substitutes, Others), Type (Knee, Ankle, Hip, Wrist & Shoulder, Spine, Others), Application (Osteoarthritis & Degenerative Arthritis, Spinal Fusion, Fracture Recovery, Soft Tissue Injuries, Maxillofacial & Dental Applications), End User (Hospitals & Ambulatory Centers, Research & Academic Institute), Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa) - Industry Trends & Forecast to 2026
proteins belong to transforming growth factor [beta] superfamily which include TGF [beta], Activin, Nodals, Inhibins and Growth Differentiation Factors (GDFs) family.
FOP is caused by a mutation in the gene for ALK2, which is known as ACVR1, that causes hypersensitivity to certain bone morphogenetic
proteins and a neomorphic response to activins.
Recombinant bone morphogenetic
protein (rhBMP) has been applied since its approval in anterior lumbar inter-body fusion in 2002.
[ClickPress, Thu Sep 27 2018] According to a new market research report "Bone Growth Stimulators Market by Product (Device, Bone morphogenetic
protein, PRP), Application (spinal fusion, Delayed Union & Non Union Bone Fracture, Dental, Maxillofacial), End User (Hospitals, Home care, Academia, CROs)Ce--CeGlobal Forecasts to 2022", published by MarketsandMarketsao.
Bioventus, a developer of orthobiologic solutions, has entered into an agreement to divest its next-generation bone morphogenetic
protein (BMP) development program to a new company formed by Viscogliosi Brothers LLC (VB), a private equity investment firm focused on developing neuromusculoskeletal technologies.
This can be achieved by inhibiting the signaling pathway of a specific protein (bone morphogenetic
Cartilage originated morphogenetic
protein-1 (CDMP) commonly recognized as Growth Differentiating Factor 5 (GDF5), is a predecessor polypeptide having 501 amino acids with seven most conserved cysteine at C-terminal.
In addition, numerous studies have revealed that bone morphogenetic
protein 15 (BMP15) is differentially expressed in small and large antral follicles during the development in vitro of cultured preantral follicles (Pramod et al., 2013; Lima et al., 2012).