mosaicism


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Related to mosaicism: chimerism

mo·sa·i·cism

 (mō-zā′ĭ-sĭz′əm)
n.
A condition in which tissues of genetically different types occur in the same organism.

mosaicism

(məʊˈzeɪɪˌsɪzəm)
n
(Genetics) the occurrence of different types of cells side by side in the same organism

mo•sa•i•cism

(moʊˈzeɪ əˌsɪz əm)

n.
a condition in which an organism or part is composed of two or more genetically distinct tissues.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mosaicism - the condition in which an organism has two or more cell populations that differ in genetic makeup
condition - a mode of being or form of existence of a person or thing; "the human condition"
Translations

mo·sa·i·cism

[MIM*158250]
n. mosaicismo, así como en un mosaico, los cromosomas son genéticamente mutadores diferentes que pueden establecer características distintas en humanos, tal como se muestra en la fisonomía por diferencias de sexo.
References in periodicals archive ?
Somatic mosaicism occurs when there is a spontaneous reversion mutation that can lead to a mixed chimerism of corrected and uncorrected bone marrow cells leading to stabilisation or correction of an FA patient's blood counts in the absence of any administered therapy.
Somatic mosaicism occurs when there is a spontaneous reversion mutation that can lead to a mixed chimerism of corrected and uncorrected bone marrow cells leading to stabilization or correction of an FA patient's blood counts in the absence of any administered therapy.
ILVEN is a hamartoma that usually is congenital or presents in early childhood; presents with linear or whorled, hyperkeratotic papules and plaque in similar linear "line of Blaschko" patterns; and represents cutaneous mosaicism.
Among the 66.7% of chromosomally abnormal 3PN embryos, all of them were 69, XXY, and 13.3% of them showed mosaicism. From previous studies, it is known that aneuploidy and mosaicism in 3PN embryos can still constitute "normal" developmental events, with an etiology as mentioned above, and not necessarily a consequence of the 3PN status.
The findings, demonstrating "age mosaicism," were published in Cell Metabolism on June 6, 2019.
ILVEN is a hamartoma that usually is congenital or presents in early childhood; presents with linear or whorled, hyperkeratotic papules and plaque in similar linear "line of Blaschko" patterns; and represents cutaneous mosaicism. It is often difficult to differentiate between lichen striatus and ILVEN; however, lichen striatus is not congenital, and is a self-limited condition.
Pallister-Killian mosaic syndrome (PKS), also termed Pallister-Killian syndrome, Pallister mosaic aneuploidy, tetrasomy 12p mosaicism, isochromosome 12p syndrome, or Teschler-Nicola syndrome is a rare dysmorphic disorder caused by mosaic tetrasomy of the short arm of chromosome 12 (12p).
A wide phenotypic variability in mixed gonadal dysgenesis has been previously described, with unilateral testicular structures, due in part to isodicentric Y(p) (idicY(p)) mosaicism or the presence of SRY in early gonadal ontogenesis of Sertoli cells (22).
The variation, called aACAysomatic mosaicism,aACAO could explain why neurons in the temporal lobe are the first to die in Alzheimer's, for example, and why dopaminergic neurons are the first to die in Parkinson's.
Genetic variability within an organism can come about due to fusion between distinct individuals (chimerism) and/or through the accumulation of mutations, resulting in genetic mosaicism (Gill et al., 1995; Barki et at., 2002).
It may be inherited, or caused by genetic mosaicism, chimerism, disease, or injury.