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They considered to be a palygenic multifactorial problem in which genetic susceptibility is influenced by multiple and probably cumulative environmental factors, interacting altogether to shift the complex process of morphogenesis of the primary and secondary palates, toward a threshold of abnormality at which clefting may occur (multifactorial/threshold model).
Its etiology is usually multifactorial, including ischemic phenomenon, chemical injury to the tissue from gastric contents, and a decrease in effective mucosal defense barriers.
At the same time, there is little economic literature on ordering institutional systems, under their multifactorial description and analysis.
Its aetiology is uncertain but is almost certainly multifactorial, including prematurity and infection.
The objective of this section of the supplement is to discuss the multifactorial pathophysiology of the overactive bladder syndrome (OAB) and translate this knowledge into the clinical environment.
Acne, a common chronic skin disorder, is of multifactorial etiology.
The mechanisms of skin ageing are multifactorial and include genetics, sun exposure, environmental stressors and more.
The researchers concluded that the pathogenesis of ATE is multifactorial and therefore treatment and prevention of this syndrome might involve drug combinations modulating hemostasis and inflammatory pathways.
Recurrent cramping tends to be a phenomenon that is a bit perplexing and probably multifactorial. There is much debate about the role of sodium and other electrolytes but sodium loss in sweat/inadequate sodium intake is most likely part of the puzzle.
A first trial did not find significant benefit of using multifactorial intervention including risk assessment, education of patients and staff, medication review, modification of environment, exercise and alarms.
"Cancer is a multifactorial disease that requires a multifactorial treatment plan: medical, nutritional, and lifestyle changes as well as mental, emotional, social, and spiritual support," assert the authors.
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