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1. Involving, dependent on, or controlled by several factors.
2. Of, relating to, or caused by a pattern of familial inheritance resulting from multiple genetic or environmental factors or from a combination of both.

mul′ti·fac·tor′i·al·ly adv.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


1. (Genetics) genetics of or designating inheritance that depends on more than one gene
2. Also : multifactor involving or including a number of elements or factors
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌmʌl ti fækˈtɔr i əl, -ˈtoʊr-, ˌmʌl taɪ-)

having or stemming from a number of different causes or influences.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.multifactorial - involving or depending on several factors or causes (especially pertaining to a condition or disease resulting from the interaction of many genes)
complex - complicated in structure; consisting of interconnected parts; "a complex set of variations based on a simple folk melody"; "a complex mass of diverse laws and customs"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


a. multifactorial, rel. a varios factores.
English-Spanish Medical Dictionary © Farlex 2012


adj multifactorial
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
They considered to be a palygenic multifactorial problem in which genetic susceptibility is influenced by multiple and probably cumulative environmental factors, interacting altogether to shift the complex process of morphogenesis of the primary and secondary palates, toward a threshold of abnormality at which clefting may occur (multifactorial/threshold model).
Its etiology is usually multifactorial, including ischemic phenomenon, chemical injury to the tissue from gastric contents, and a decrease in effective mucosal defense barriers.
At the same time, there is little economic literature on ordering institutional systems, under their multifactorial description and analysis.
Its aetiology is uncertain but is almost certainly multifactorial, including prematurity and infection.
The objective of this section of the supplement is to discuss the multifactorial pathophysiology of the overactive bladder syndrome (OAB) and translate this knowledge into the clinical environment.
Acne, a common chronic skin disorder, is of multifactorial etiology.
The mechanisms of skin ageing are multifactorial and include genetics, sun exposure, environmental stressors and more.
The researchers concluded that the pathogenesis of ATE is multifactorial and therefore treatment and prevention of this syndrome might involve drug combinations modulating hemostasis and inflammatory pathways.
Recurrent cramping tends to be a phenomenon that is a bit perplexing and probably multifactorial. There is much debate about the role of sodium and other electrolytes but sodium loss in sweat/inadequate sodium intake is most likely part of the puzzle.
A first trial did not find significant benefit of using multifactorial intervention including risk assessment, education of patients and staff, medication review, modification of environment, exercise and alarms.
"Cancer is a multifactorial disease that requires a multifactorial treatment plan: medical, nutritional, and lifestyle changes as well as mental, emotional, social, and spiritual support," assert the authors.
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