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 (mŭl′tē-no͞o′klē-ər, -nyo͞o′-, -tī-)
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌmʌltɪˈnjuːklɪə) ,




(Biology) (of a cell, microorganism, etc) having two or more nuclei
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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References in periodicals archive ?
As Shoemaker's work has progressed on the complex problems of grey matter nuclear atrophy, a small but growing cohort of patients with multinuclear atrophy and cognitive impairment have led to improvements that may have application to illnesses such as Alzheimer's disease.
Multinuclear cells emerged after culture in differentiated media for 12 days.
The results of cytokeratin staining were as follows: microscopic examination revealed large geographic tumor necrosis, multinuclear and mononuclear giant cells, and atypical mitosis.
Excisional biopsy revealed well-circumscribed subcutaneous tissue including widespread dystrophic calcification and multinuclear giant cells.
(13) The proliferating tumor cells recapitulate chorionic villous trophoblasts of various types and are organized in biphasic to triphasic growth patterns: sheets or cords of mononuclear tumor cells (large, intermediate trophoblasts with abundant amphophilic to eosinophilic cytoplasm and/ or smaller cytotrophoblasts) rimmed by layers of multinuclear syncytiotrophoblastic cells (Figure 1).
In the histopathological examination of the prepared sections, we found lobule-restricted, non-caseous granulomas involving lymphocytes, plasma cells, epithelioid histiocytes and multinuclear giant cells and neutrophil assemblages in the middle; and neoplastic epithelial cell proliferation in 4 different foci, the largest being 0.7x0.4 cm in diameter, limited to the ductal lobular system.
Bone marrow reticulum also contained epitheloid histiocytes and multinuclear phagocytes and hystiocytes.