The company said DEB and RDEB are rare genetic multisystem
disorders associated with severe skin blistering and treatment is currently limited to palliative symptom management.
Both of these systems are popular in central office, cable multisystem
operator (MSO), mobile telephone switching office and data center applications.
An increasing body of clinical evidence suggests that SMA is a multisystem
disorder, and the loss of SMN protein may affect many tissues and cells beyond the central nervous system.
involvements in genetic defects are not uncommon and extracutaneous manifestations have been reported in many of the cases of LWNH, neurological abnormalities being the most common.
Second, for years the patient was not regarded as having a MID as his family history was incomplete because of difficulties taking it and since nobody regarded the clinical presentation of the patient as indicative of a MID and since it is not well-known that MIDD is not only characterized by diabetes and deafness but in fact a multisystem
disease as most of the MIDs.
The syndromic forms of congenital SA are usually part of multisystem
mitochondrial dysfunction disorders and include Pearson marrow pancreas syndrome, MELAS (myo-encephalopathy, lactic acidosis and stroke like episodes), Kearn-Sayre syndrome and MLASA (myopathy, lactic acidosis and sideroblastic anemia)2,3.
These are patients who, after a thorough work-up, have a normal CBC, skeletal survey, and liver function tests; essentially, no evidence of multisystem
The Los Angeles coroner's office attributed his death to 'multisystem
organ failure' due to a 'mixed toxicity' of seven medications.
Langerhans Cell Histiocytosis (LCH) is an uncommon multisystem
disorder of unknown etiology, characterized by accumulation of histiocytes in various tissues.
The experimental results related to the proposed multicamera multisystem
calibration methodology are presented next.
The course of LCH is variable and can range from a self-limited, asymptomatic, localized lesion to a disseminated multisystem
disease with a less favorable prognosis.