Also found in: Medical.


 (mŭl′tē-sĭ-stĕm′ĭk, -stē′mĭk, -tī-)
Relating to a disease or condition that affects many organ systems of the body.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
The pervasive and progressive accumulation of GAGs leads to significant morbidities and multisystemic clinical impairments resulting in diminished functional capacity, impaired quality-of-life and early mortality.
Considering the multisystemic effects of thyroid stimulating hormone (TSH), it is reasonable to expect consequences resulting from inappropriate treatment.
Porcine circovirus type 2 is mainly linked to post-weaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS), as well as reproductive disorders, including fetal mummification (ASANOME et al., 2008; MAES et al., 2008; MADSON et al., 2009).
Faponle noted that kidney disease is progressive and multisystemic in its manifestation, adding that the body can get swollen and needs a definitive diagnostics.
This guide describes home-based family therapy and school-based interventions with at-risk students using a multisystems model that helps adolescents and families with multiple problems focus and prioritize their issues, in addition to multisystemic therapy that incorporates multisystemic levels in treatment.
Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation.
All and all, weight problems and their related food addictions and allergies are not isolated gastrointestinal or caloric problems, but one of a multisystemic chronic disease of the entire body.
We emphasize that in case of different multisystemic findings, such as ichthyosis, hearing loss, hepatomegaly, splenomegaly, cirrhosis, cataract, keratopathy, myopathy, and mental retardation, physicians should suspect Chanarin Dorfman syndrome.
Services include adoption, pregnancy care, foster care, counseling, residential treatment for abused and neglected children, multisystemic therapy for at-risk youth, independent living for adults with developmental disabilities, and assisted living and employment assistance for low-income seniors.
BD is a rare multisystemic chronic inflammatory disease of unknown etiology, first described in 1937.[1] It is suggested that there may be a genetic predisposition (human leukocyte antigen [HLA], HLA-B51) and that certain microorganisms may play a role.
The basis of the intervention was a family and ecologically-based treatment model called Multisystemic Therapy (MST; Henggeler, Schoenwald, Borduin, Rowland, & Cunningham, 2009).