mutant gene

Also found in: Thesaurus, Medical, Encyclopedia.
Related to mutant gene: Mutant allele
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mutant gene - a gene that has changed so that the normal transmission and expression of a trait is affected
cistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
CFTR, cystic fibrosis transport regulator - the gene that is mutated in cystic fibrosis
References in periodicals archive ?
BB-301 is a single vector (gene therapy construct) system which uses ddRNAi to silence expression of the mutant gene associated with OPMD, while simultaneously adding back a copy of the normal version of the same gene to restore gene function.
When Donaldson found out she did not carry the mutant gene, she felt both gratitude and relief.
Northwestern University researchers have partnered with Japan's Tohoku University to develop and test an experimental drug that would inhibit the action of PAI-1, like in Amish people with the mutant gene.
Scientists found that the mutant gene, ApoE4, is directly linked to brain damage caused by knots of protein within neurons called tau tangles.
The mutant gene, ApoE4, has been directly linked to brain damage caused by knots of protein within neurons called tau tangles.
The new study found that human embryos effectively repair these breaks in the mutant gene using the normal copy of this gene from a second parent as a template.
TWO sisters who underwent mastectomies to slash their chances of developing cancer are raising cash to help scientists learn more about the mutant gene that has plagued their family.
Another American research team has found people with a mutant gene were more likely to develop both type 2 diabetes and Alzheimer's.
In one of her blood-forming stem cells, the chromosome carrying the mutant gene had shattered (illustrated above) and reassembled Humpty-Dumpty style, leaving out some genes, the researchers report in the Feb.
The researchers completed a "proof of concept" experiment in which they created a break in the DNA strands of a mutant gene in mouse cells, then repaired the DNA through a process called homologous recombination, replacing flawed segments with correct ones.
35pm When a cure is found for the mutant gene, tensions rise and Magneto pre-empts a war with humans, planning to strike first.
When the samples from mice with bowel tumours were transferred to other healthy animals with a mutant gene called Kras (that is associated with bowel cancer), this was enough to trigger cancer even in the absence of a high-fat diet.