mutant gene


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Related to mutant gene: Mutant allele
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mutant gene - a gene that has changed so that the normal transmission and expression of a trait is affected
cistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
CFTR, cystic fibrosis transport regulator - the gene that is mutated in cystic fibrosis
References in periodicals archive ?
These B-ALL cases have a chromosomal rearrangement that creates a mutant gene. That gene fuses a segment of the IGH gene with part of the oncogene DUX4, CRLF2 or another gene.
BATH, U.K., February 28, 2019 -- Scientists here have identified a mutant gene in fish that is involved in controlling stem cells.
According to reports, geneticists from the University of Geneva Medical School (UNIGE) and the Liaquat University of Medical and Health Sciences, Jamshoro, have analysed the genome of many families having the mutant gene, in a new gene called MARK3.
So for our recently published study we wanted to better understand the effects of the mutant gene on brain cells before the onset of symptoms.
Professor Stylianos Antonarakis said, "In our attempts to uncover new recessive genetic disorders, we looked at families where there was consanguineous marriage and where both parents carried one copy the mutant gene and passed it on to the child."
Voyager presented results for VY-SOD101, which targets the superoxide dismutase 1 gene, the first mutant gene discovered to be causal for the development of amyotrophic lateral sclerosis.
BB-301 is a single vector (gene therapy construct) system which uses ddRNAi to silence expression of the mutant gene associated with OPMD, while simultaneously adding back a copy of the normal version of the same gene to restore gene function.
When Donaldson found out she did not carry the mutant gene, she felt both gratitude and relief.
Northwestern University researchers have partnered with Japan's Tohoku University to develop and test an experimental drug that would inhibit the action of PAI-1, like in Amish people with the mutant gene.
Scientists found that the mutant gene, ApoE4, is directly linked to brain damage caused by knots of protein within neurons called tau tangles.
The mutant gene, ApoE4, has been directly linked to brain damage caused by knots of protein within neurons called tau tangles.
Using an enzyme called Cas9, it is possible to snip a specific target sequence on a mutant gene. The new study found that human embryos effectively repair these breaks in the mutant gene using the normal copy of this gene from a second parent as a template.