The onset of symptoms is sudden, with fever, myalgia
, (muscle ache), dizziness, neck pain and stiffness, backache, headache, sore eyes and photophobia (sensitivity to light).
Statins can lead to myalgia
(muscle pain), myopathy, elevated creatin in ekinase (myonecrosis) and rhabdomyolysis.4,5 Studies have reported that muscle and tendon related side effects were most commonly noticed in patients treated with rosuvastatin while pravastatin and lovastatin have the lowest rate of side effects.6 Onset of myalgia
varies from patient to patient and starts after a few weeks to years of statin therapy.7 Myalgia
could be generalised or localised, and persists for more than 3 months after discontinuation of statin therapy with average duration of six-and-a-half months.8
Grade 3 AEs were reported in 54.7% patients, with the most frequent being anemia, myalgia
, cellulitis, pleural effusion, and pneumonia; Discontinuation due to AEs occurred in 18.9% patients with two determined to be related to study drug; and There were five deaths due to AEs, which were all determined by the investigators to be unrelated to zanubrutinib treatment.
Symptoms, such as myalgia
and ELE, are less frequent findings of the disease. In this article, we present an atypical FMF case with myalgia
and skin lesion symptoms alone, but not with typical episodes of the disease.
Geeny Anne Austria of the DOH-CAR RESU explained that leptospirosis is a group of zoonotic bacterial disease with variable manifestations and it is characterized by the sudden onset of fever, headache, chills, severe myalgia
in calves and thighs and conjunctiva suffusion.
No statistically significant effects on myopathy, myalgia
, or rhabdomyolysis were found among the RCTs.
Regarding the additional cases recorded today, the first case involves a 55-year-old male patient with underlying illnesses, who developed fever, headache, cough and myalgia
since August 10.
reported a case of microscopic polyangiitis (MPA) presenting with myalgia
and weakness at the proximal extremities, which was finally diagnosed as vasculitis of the muscle and lung (3).
Further, the infected people initially develop influenza-like symptoms of fever, headaches, myalgia
(muscle pain), vomiting and sore throat, which could be followed by dizziness, drowsiness, altered consciousness, and neurological signs that indicate acute encephalitis.
* Non-inflammatory Myalgia
: Local muscle soreness resulting from continued protective co-contraction.
He urged the public to seek medical assistance if they experience high fever, headache, cough, myalgia
and joint pain for more than 24 hours.
Statin-associated myopathy or myalgia
is a well-known side effect of lipid-lowering agents.