[USA], August 3 (ANI): Mycobacteria
, a bacterial group that causes killer diseases such as tuberculosis (TB), leprosy, and Buruli ulcer depend on carbon monoxide to survive when other nutrients are not available, suggests a new study.
Preclinical in vitro and in vivo studies have demonstrated the potency of SPR720 against clinically important mycobacteria
, including NTM species Mycobacterium avium complex and Mycobacterium abscessus, as well as Mycobacterium tuberculosis.
Approximately 75 species of rapidly growing mycobacteria
(RGM) have been isolated from soil, animals, and water (7).
In recent decades, increasing incidence of non-tuberculous (also called "atypical") mycobacteria
infections has been reported, and those caused by M.
(NTM) include all Mycobacterium species excluding M.
Fifty-two clinical isolates of mycobacteria
from human patients were randomly selected to evaluate the genetic diversity in MTBC.
We hypothesized that the patient's chemical injury to his hand likely provided an opportunity for the mycobacteria
to penetrate his skin.
In sections on general considerations, clinical syndromes, and nontuberculous mycobacteria
, it examines such aspects as laboratory diagnosis and susceptibility testing for Mycobacterium tuberculosis, the role of surgery in the diagnosis and management of tuberculosis, central nervous system tuberculosis, cardiovascular tuberculosis, tuberculosis associated with HIV infection, and Mycobacterium bovis and other uncommon members of the Mycobacterium tuberculosis complex.
are the cause of opportunistic infections and frequently presents with similar clinical features like tuberculosis so species identification is important for management.
The paper presents the study of the habitat of mycobacteria
in various natural and climatic zones of the Karaganda region, which showed that out of all the isolated cultures, 307 (94.5%) were atypical mycobacteria
The company has received the grant to study the treatment of two pulmonary non-tuberculous mycobacteria
infections - Mycobacterium avium and Mycobacterium abscessus - with the company's inhaled Linhaliq and Lipoquin products.