Histological examination suggested myelinisation
in the proximal nerve stump that decreased gradually in the middle and distal parts of the nerve.
In addition to the connectivity analysis measures of grey matter vitality, myelinisation
, susceptibility maps and potentially maps of iron distribution will be made available.
La valeur du FA est sensible au degre de myelinisation
, au diametre moyen des fibres et a l'organisation axonale (Paus, 2010).
In this way, the myelinisation
of this area is not complete until the age of 20 years old, and experimental injury of this area at young monkeys does not generate immediate cognitive impairments, instead it decreases the ability to perform some cognitive tests involving retention of certain aspects for a long period.
These results are supported by the association between speed of processing and axonal myelinisation
of the central nervous system (Posthuma et al., 2001), and by the finding of shared genetic components in the correlation between processing speed and general cognitive ability (Finkel & Pedersen, 2000).
The process of normal fetal brain development, neuronal multiplication, migration, and structural organization (4, 5) mainly occurs in the second trimester when the fetus is primarily supplied with maternal thyroid hormones.brain development from the beginning of third trimester involves glial cell multiplication, migration and myelinisation
, using primarily the fetal supply of thyroid hormone.
The development of the CC has been described to begin at approximately 8 to 10 weeks of gestation.11,12 Number of collosal fibers are fixed at birth, however, structural changes at corpus collosium continues due to myelinination of fibers during postnatal devolopment, redirection, pruning and myelination.13 The complete formation of CC continues to enlarge throughout infancy, childhood, and young adulthood.14 Schaefer et al stated that growing of CC continues till the 15 year age and during this period it could be reflections of increasing the myelinisation
of CC.15 On the other
Differentiated neuroglia cells are very sensitive to the deficiency of oxygen in the neonatal period, its defeat in the specified period leads to the disorders of myelinisation
. Selective necrosis of neurons is determined by various sensitivity of brain cellular elements to hypoxia.