DS, also known as severe myoclonic
epilepsy in infancy, is an orphan disease considered one of the most intractable forms of epilepsy, with first seizures occurring during the first year of life.
Ysgol Maes Garmon pupil Katie Potter, 13, from Northop, Flintshire, was diagnosed with juvenile myoclonic
epilepsy around April 2018.
She added: "He will continuously twitch and jerk, which are known as myoclonic
The literature has described clozapine-induced generalized tonic-clonic, myoclonic
, simple and complex partial, and absence seizures.
A few months later, I received a diagnosis - juvenile myoclonic
Conclusion: Majority of patients had symptomatic infantile spasms and generalized tonic clonic along with myoclonic
jerks were predominant seizure types.
"The Tonic Clonic seizures and myoclonic
seizures are uncontrollable and relentless, meaning that no emergency intervention is working to stop the continuous seizures.
Early diagnosis of severe myoclonic
epilepsy in infancy.
Background: Treatment of myoclonic
seizures in myoclonic
epilepsy with ragged-red fibers (MERRFs) has been empirical and ineffective.
Later, other types of seizures typically arise, including myoclonic
seizures (involuntary muscle spasms).
Dravet syndrome, also known as severe myoclonic
epilepsy in infancy (SMEI), is a catastrophic early onset epileptic syndrome that is thought to affect approximately 2,000 to 8,000 patients in the US.