Abnormal ocular alignment frequently results from damage to the intranuclear portion of the gaze system, including: cranial nerves (CN) III (oculomotor), IV (trochlear), and VI (abducens), or the
myoneural junction or extraocular muscles they innervate.
Combined involvement of muscle, nerve, and
myoneural junction following Leptospira infection.
Tetanospasmin then enters the nervous system peripherally at the
myoneural junction and is transported centripetally into neurons of the central nervous system (CNS).
In addition, the neonatal
myoneural junction appears to demonstrate an increased sensitivity to this class of agents.
(20) Initial bradycardia, bradypnea, and recumbency were likely related to effects of envenomation on vascular endothelium, peripheral nerve endings, and
myoneural junctions, (21) as opposed to an allergic or anaphylactic reactions, which generally demonstrate tachycardia.
Procaine, pentobarbital and halothane: effects on the mammalian
myoneural junction.
