Iqbal et al., "DNA counterion current and saturation examined by a MEMS-based solid state nanopore
sensor," Biomedical Microdevices, vol.
Another platform that holds great promise for the PoC sector is the platform developed by Oxford Nanopore
During the Ebola epidemic, Oxford Nanopore
's pocket-sized genetic sequencing technology was used in the field in Guinea to sequence the virus within 24 hours.
A molecular dynamics model of bulk-nanopore-bulk, which is similar to a nanopore
in a cell membrane, as shown in Figure 1, was modeled for different concentrations of solution using a modified TINKER 4.2  MD package.
By using an electrical pulse to create a temporary nanopore
in a cell membrane, researchers can deliver chemicals, drugs, and DNA directly into a single cell.
12 August 2014 - UK nanopore-based electronic systems developer Oxford Nanopore
Technologies Ltd unveiled today it had secured GBP35m (USD59m/EUR 44m) in new investment via a private share placement.
As a complex organic material with a complicated porous structure, coal has been studied by many researchers on the relationships between the macromolecular structure and the nanopore
The result was in agree with previous works that rising calcinating temperature could also densify the shell of MSS [5, 19], implying that rising temperature and prolonging time have similar effects on the nanopore
structure in the shell of MSS.
Among the topics are a single-molecule barcoding system using nanoslits for DNA analysis called nanocoding, inserting and manipulating DNA in a nanopore
with optical tweezers, analyzing biomolecules using surface plasmons, small-angle scattering and neutron contrast variation for studying biomolecular complexes, imaging quantum dots in vivo, the monitoring and affinity purification of proteins using dual tags with tetracysteine motifs, magnetic nanoparticles for local drug delivery using magnetic implants, and custom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes.
His group analyses DNA and RNA molecules and has developed a biomolecular nanopore
detector that can discriminate between almost identical strands of DNA.
Individual writings include "Nanopore
Methods for DNA Detection and Sequencing", "Engineering Gene Circuits: Foundations and Applications", "Nanotechnologies in Adult Stem Cell Research", and much more.
Unrelated to the BioTrove collaboration, Applied Biosystems has invested in VisiGen's single-molecule technology (see IBO 10/31/05) and Eagle Research and Development's nanopore
technology (see IBO 1/31/07).