necrobiosis lipoidica


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Noun1.necrobiosis lipoidica - skin disease marked by thin shiny patches (especially on the legs); often associated with diabetes mellitus
disease of the skin, skin disease, skin disorder - a disease affecting the skin
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References in periodicals archive ?
M2 EQUITYBITES-October 3, 2018-Processa Pharmaceuticals wins US FDA clearance to start Phase 2 clinical development of PCS-499 in patients with Necrobiosis Lipoidica
Global Banking News-October 3, 2018-Processa Pharmaceuticals wins US FDA clearance to start Phase 2 clinical development of PCS-499 in patients with Necrobiosis Lipoidica
M2 PHARMA-October 3, 2018-Processa Pharmaceuticals wins US FDA clearance to start Phase 2 clinical development of PCS-499 in patients with Necrobiosis Lipoidica
Winkelmann, "Necrobiosis Lipoidica Diabeticorum: A Clinical and Pathological Investigation of 171 Cases," JAMA Dermatology, vol.
Cutaneous manifestations of diabetes are classified into four categories: Skin lesions with strong-to-weak association to diabetes (necrobiosis lipoidica, diabetic dermopathy, diabetic bullae, yellow skin, eruptive xanthomas, perforating disorders, acanthosis nigricans, oral leucoplakia, lichen planus), infections (bacterial, fungal), cutaneous manifestations of diabetic complications (microangiopathy, macroangiopathy, neuropathy) and skin reactions to diabetic treatment (Sulphonylureas or insulin).
Our findings that FXIII-A marks the alternative activation pathway in macrophages is best reflected in diseases of granuloma annulare (GA) and necrobiosis lipoidica (NL), which are the prime examples of noninfectious, nonmalignant inflammatory skin diseases with granuloma formation.
Necrobiosis lipoidica diabeticorum (NLD) is a disorder involving subcutaneous collagen degeneration that results in thickening of blood vessel walls, fat deposition, and the formation of granulomas.