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Related to nedocromil: cromolyn sodium, nedocromil sodium


An anti-inflammatory drug, C19H15N, used in an inhaler in the form of a sodium salt to treat mild-to-moderate asthma.

[ne- (perhaps from 9-ethyl, beginning of the chemical name, referring to the presence of an ethyl group in ninth position) + d(i)- + o(xy)- + shortening and alteration of cromolyn.]
References in periodicals archive ?
These include cromolyn, nedocromil, leukotriene modifiers, and antihistamines (Woo, 2016).
Long-term effects of budesonide or nedocromil in children with asthma.
Second, there was specific phenomenon that researchers were enthusiastic about asthma therapy, and glucocorticoid [100] and nedocromil sodium [101] were often studied using pulmonary function test.
sodium cromoglycate, nedocromil sodium, pemirolast, and lodoxamide; (3) Dual acting agents - they have both antihistaminic and mast cell stabilizing properties, e.g., olopatadine, ketotifen, azelastine, and epinastine; (4) Non-steroidal anti-inflammatory drugs, e.g., ketorolac, diclofenac, and flurbiprofen; (5) Corticosteroids, e.g., prednisolone, hydrocortisone, fluorometholone, loteprednol, and desonide.
There are three drugs in this class that can be used topically in the eye: cromolyn, lodoxamide (Alomide), and nedocromil (Alocril).
Nedocromil sodium exerts its anti-inflammatory and anti-asthmatic effect by inhibiting the activation and activity of multiple inflammatory cells, including mast cells, eosinophils, airway epithelial cells and sensory neurons.
(1) Eleven trials that included 899 children and adults compared mast cell stabilizers (sodium cromoglycate, nedocromil, and lodoxamide tromethamine) with placebo.
Ozone-induced mediator release from human bronchial epithelial cells in vitro and the influence of nedocromil sodium.
Drugs, such as sodium cromoglycate, nedocromil sodium, pemirolast, and lodoxamide act by stabilizing mast cells.
As with VKC, AKC requires long-term therapy with topical mast cell stabilisers such as sodium cromoglycate, lodoxamide and nedocromil to treat the allergic inflammation in mild cases.
G protein-coupled receptor-35 (GPR35) has been shown to be a target of the asthma drugs cromolyn disodium and nedocromil sodium.