neoarsphenamine


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neoarsphenamine

(ˌniːəʊɑːsˈfɛnəˌmiːn; -fɪˈnæmɪn)
n
(Pharmacology) a derivative of arsenic formerly used in treating syphilis
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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The introduction of this drug, arsphenamine (Salvarsan), and its chemical derivative neoarsphenamine (Neosalvarsan) in 1910 ushered in a complete transformation of syphilis therapy and the concept of chemotherapy.
Rabbit Syphilis has been successfully treated using Neoarsphenamine (Horvath et at., 1980), Chloramphenicol (Saito et at., 2003; Saito and Hasegawa 2004), Penicillins --Benzathine penicillin G (Horvath et at., 1980; Cynthia, 2005).
The formal clinical trial is actually an outgrowth of the Cooperative Clinical Trials of the 1920's for evaluating neoarsphenamine (a later version of Ehrlich's 606) for the treatment of syphilis.