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1. A crystalline compound, C15H10O2, that is a derivative of coumarin and an isomer of flavone.
2. Any of a class of flavonoid plant metabolites derived from neoflavone.
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References in periodicals archive ?
odorifera species, a flavanone eriodictyol (22) and a neoflavone 3'-hydroxymelanettin (56) exhibited stronger activity than commonly used synthetic antioxidant butylated hydroxytoluene (BHT), as far as compounds 16-17, 23-24, and 35 in all three methods: oil stability index (OSI), potassium ferricyanide reducing power, and 2,2-azinobis(3-ethylbenzothiazoline- 6-sulfonate) radical ([ABTS.sup.*+]) scavenging [33].
First of all, a neoflavone derivative 57 gave cell viability with the concentration range of 10-80 [micro]M, in which the amounts of NO, PGE2, TNF-[alpha], and IL-1[beta] production, iNOS and COX-2 expressions, IkB-[alpha] phosphorylation and degradation, NF-[kappa]B (p65) translocation, and NF-kB DNA-binding activity were reduced with increasing concentration of compound 57 from 10 to 80 [micro]M in LPS (1 [micro]g/mL) stimulated primary murine peritoneal macrophages, whereas the same results were found in the concentration range of 5-40 [micro]M for 4,2',5'-trihydroxy-4'-methoxychalcone (67) [37, 45].
[sup.13]C NMR data, with the corresponding literature, suggested that 3 exhibited the skeletons of a neoflavone and a chalcone [19, 20].