neuraminidase


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Related to neuraminidase: sialic acid, Neuraminidase inhibitor

neu·ra·min·i·dase

 (no͝or′ə-mĭn′ĭ-dās′, -dāz′, nyo͝or′-)
n.
A hydrolytic enzyme that removes sialic acid from glycoproteins and is found in many cells and viruses. It occurs on the surface of influenza viruses and enables the release of newly replicated viruses from infected cells.

[neuramin(ic acid) (neur(o)- + amin(e)) + -id(e) + -ase.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

neuraminidase

(ˌnjʊərəˈmɪnɪdeɪz)
n
(Biochemistry) any of various enzymes, found esp in viruses, that catalyse the breakdown of glucosides containing neuraminic acid, an amino sugar
[C20: from neuramin(ic acid) (from neuro- + amine + -ic) + -ide + -ase]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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References in periodicals archive ?
The conserved protein, called M2, is dwarfed by its neighbors, hemagglutinin and neuraminidase. These capricious, larger molecules have made the flu virus a moving target.
KF918334-KF918341), whereas the sequence analysis of the other 2 samples was focused on hemagglutinin and neuraminidase genes and a few regions of the other genes (nt 159-525 and nt 994-1107 of polymerase basic protein [PB] 2, nt 115-453 and nt 1726-2259 of PB1, nt 19-297 of nucleocapsid protein, and nt 715-981 of matrix protein) to trace the avian virus responsible for the human infections.
neuraminidase inhibitor approved in the US for the treatment of acute uncomplicated influenza in adults.
They have described how to use their newly discovered compounds to interrupt the enzyme neuraminidase's facilitation of influenza's spread.
The neuraminidases of HiNi viruses also are similar to a neuraminidase in the current vaccine strain.
Amantadine and rimantadine are approved for treating influenza A, while the neuraminidase inhibitor drugs zanamivir and oseltamivir are approved to treat both influenza A and B [6-8].
One viral protein, an enzyme called neuraminidase, is required for the bundle to unglue itself so that individual virus particles can infect other cells.
Biota Pharmaceuticals Inc and Daiichi Sankyo had entered into a collaboration, commercialisation and license agreement to develop long-acting neuraminidase inhibitors, including laninamivir octanoate, under which, Daiichi Sankyo has obtained exclusive marketing rights to laninamivir octanoate in Japan.
Oseltamivir, an orally administered neuraminidase (NA) inhibitor, is the most prescribed medication for the treatment of persons with influenza virus infections.
Neuraminidase inhibitors (NAIs) are recommended for the control of severe influenza A and B infections (1).