MAG has also been shown as a neurite
outgrowth inhibitor in vitro , and the increased MAG expression may inhibit axonal germination and regeneration. In this study, the expression of CCND1 significantly decreased after silencing of Wnt5a expression, whereas the expression of MAG markedly increased.
In patient-derived neurons, reduced neurite
length as well as elevated oxidative stress and apoptosis were observed compared to neurons derived from healthy controls.
(18) reported that the IncRNA uc.217 modulates neurite
outgrowth of DRG neurons after sciatic nerve injury.
The researchers have now closed this gap with the aid of so-called neurite
orientation dispersion and density imaging.
Some psychedelics tested, including LSD, proved to be more potent and efficacious than ketamine in promoting neurite
Mark Tuszynski's lab, with colleagues in Germany and Singapore, monitored neurite
outgrowth from NPCs and NSCs growing on a myelin substrate in Petri dishes.
They assess, for instance, the proliferation and differentiation of neuronal precursor cells (Baumann et al., 2016; Culbreth et al., 2012; Fritsche et al., 2005; Hogberg et al., 2010, 2009; Schmuck et al., 2017; Shinde et al., 2017; Balmer et al., 2012), the loss of certain neuronal (sub)populations (Baumann et al., 2016; Culbreth et al., 2012; Pamies et al., 2016; Schmuck et al., 2017; Zimmer et al., 2011b,a), or the impairment of migration (Nyffeler et al., 2017b; Schmuck et al., 2017; Zimmer et al., 2012), neurite
outgrowth (Harrill et al., 2011; Krug et al., 2013) or neuronal network formation (Brown et al., 2017; Pamies et al., 2016; Schmuck et al., 2017).
They also produce certain components of the tissue that forms around grafted cells, facilitating neurite
Specifically for neural tissue regeneration, graphene has demonstrated the ability to perform as an effective platform compatible with neural cells or their precursors  and promoted neurogenesis, as assessed by neurite
sprouting and neural network formation [14,16].
), consisting of 150 areas of micropillars with variable diameter and spacing on the neurite
outgrowth and directionality of immature PSC neuronal progeny.
Purified HB-GAM promotes the attachment of a variety of cells and is a potent inducer of neurite
outgrowth from embryonic or early postnatal cortical neurons .
The results show that the growth on the conductive substrate can enhance neurite
growth under electrical stimulation [12-14].