Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.


 (no͝or′ə-fĭl′ə-mənt, nyo͝or′-)
Any of the long, fine threads that make up a neurofibril.

neu′ro·fil′a·men′tous (-mĕn′təs) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Presentations include complete Phase III results from the SAkuraStar study investigating satralizumab for the treatment of neuromyelitis optica spectrum disorder (NMOSD), and new multiple sclerosis (MS) research, which provides insights into disease progression, including data from OCREVUS[R] (ocrelizumab) trials that advance understanding of neurofilament light chain (NfL) levels as a potential biomarker for predicting disability outcomes.
Uman is widely recognised to possess the leading antibodies available to measure neurofilament light and has become the provider of choice for biopharmaceutical and diagnostic applications.
3B), and negative for other markers (NSE, neurofilament, GFAP).
Jucker and his colleagues monitored the development of neurofilament concentration in these individuals from year to year.
Additionally, the increase in neurofilament light chain proteins precisely matched the speed at which the precuneus - which plays a role in memory - thinned and shrank.
Neurofilament accumulation in giant axons was detected by electron microscope [Figure 1]d-1f].{Figure 1}
Chitinase-3-like-1 predicted long-term cognitive impairment 1 the PASAT test, and neurofilament light-chain (NfL) predicted long-term disability in the MS severity scale and nine-hole-Peg-test (57).
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature.
Merkel cells are located in the epidermis and contain cytokeratin only, whereas the malignant counterpart MCC contains both cytokeratin and neurofilament proteins and located in the dermis of skin.
The search continues for a validated blood-based biomarker, including neurofilament light protein, plasma amyloid beta, and plasma tau.
measured osteopontin (OPN: biomarker for inflammation) and neurofilament heavy chain (NfH: biomarker for axonal injury) in patients with acute optic neuritis and sex- and age-matched healthy controls.
Immunoreactivity for neurofilament is also observed (Figure 2(f)).