neuromuscular blocking agent


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Noun1.neuromuscular blocking agent - a substance that interferes with the neural transmission between motor neurons and skeletal muscles
blocking agent, blocker - a class of drugs that inhibit (block) some biological process
Flaxedil, gallamine - neuromuscular blocking agent (trade name Flaxedil) used as a muscle relaxant in the administration of anesthesia
curare, tubocurarine - a toxic alkaloid found in certain tropical South American trees that is a powerful relaxant for striated muscles; "curare acts by blocking cholinergic transmission at the myoneural junction"
References in periodicals archive ?
Table One: Sample list of neuromuscular blocking agents available in Canada Generic Name Common Trade Name atracurium Tracrium cisatracurium Nimbex mivacurium Mivacron pancuronium Pavulon succinylcholine ([dagger]) Quelicin ([dagger]) tubocurarine Tubarine vecuronium Norcuron ([dagger]) Depolarizing neuromuscular blocking agent.
Neuromuscular blocking agents should only be prescribed after other means of decreasing oxygen consumption, managing ventilation, treating muscle spasms, and moderating intracranial pressure have proven ineffective.
Rocuronium (RO) and vecuronium (VE) are widely used aminosteroidal non-depolarizing neuromuscular blocking agents. There are few methods published for the determination of VE, its metabolite 3-desacetyl-vecuronium (OHV) (1-4), and RO (5,6) that use HPLC with ultraviolet, fluorescence, or electrochemical detection or gas chromatography with nitrogen-sensitive detection.
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
It is a widespread belief among anaesthesiologists that the spontaneous recovery of neuromuscular blocking agents (NMBA) may be sufficient to avoid postoperative residual paralysis (PORP), if enough time has passed since the last NMBA administration.
The combination of propofol and a short-acting opioid during induction of anaesthesia has been found to permit tracheal intubation without the use of neuromuscular blocking agents in paediatric patients (13-15).
Therefore Rocuronium almost fulfilling the criteria for ideal neuromuscular blocking agents for endotracheal intubation.
Using the modified up-and-down method, this study shows that the SLIPA requires a lower E[C.sub.50] of remifentanil for successful insertion than the LMA during induction with propofol TCI of 3.5 [micro]g x [ml.sup.-1] without a neuromuscular blocking agent in adults.
Neuromuscular blocking agents are most common agents leading to anaphylaxis perioperatively.
Suxamethonium is generally considered to be the primary choice for neuromuscular blocking agent during ECT, as it has a short duration of action (4).
The decision in this case to use an intermediateacting neuromuscular blocking agent for a short case on a potentially threatened airway was facilitated by the availability of a highly effective, speedy and safe reversal agent.