In all patients, IHC analysis for VSBV-1 antigen showed areas of widespread neuropil
, cytoplasmic, and nuclear staining (Figure 3, panel A).
Areas with neuropil
like material noted and foci of necrosis also seen.
The slow [K.sup.+] dependent responses were restricted to the neuropil
, further supporting their involvement in synaptic signaling (Yarowsky and Carpenter, 1978b).
The central area of a ganglion consists of neuropil
, a tangle of neuronal fibers (Fig.
Histologically, there was neuropil
edema and hemorrhage in the white matter scattered in several areas of the telencephalon (Figure 1C) and near the hemorrhagic areas foci of malacia, reactive astrocytes and some inflammatory cells were observed (Figure 1C).
The neuroectodermal cells were polygonal to spindle shaped, haphazardly arranged in short palisading bundles, streams, or disorganized poorly delineated aggregates, separated by a finely fibrillar, tangled, pale eosinophilic matrix reminiscent of neuropil
. These cells had indistinct cell borders, a small-to-moderate amount of eosinophilic cytoplasm, a round-to-oval nucleus with vesicular-to-coarsely stippled chromatin, and 1-3 inconspicuous-to-large nucleoli.
Part of the apparent change in cellularity is due to age-related changes in the size and shape of ganglion cells and the amount of intervening neuropil
. Even if the number of ganglion cells per ganglion remains stable with age, individual ganglion cell somata enlarge, (21-23) which can influence the number of cytoplasmic profiles likely to be transected in a section of given thickness.
Tumors, such as pineal parenchymal tumors, craniopharyngiomas, and hemangioblastomas, as well as ependymomas of the spinal cord, often incite reactive gliosis and Rosenthal fiber formation in the adjacent neuropil
, sometimes leading to the misrecognition of the tumor as PA.
Kerlinsky: I agree with you about using certain adjunctive pharmacotherapies for acute psychosis, which is associated with neuroinflammation, oxidative stress, and neuropil
and myelin damage.
A critical innovation is that knowledge is to be distinguished from mere information partly by the "condensed state of the global cortical neuropil
A: Low-power histology of the mass (hematoxylin and eosin stain, original magnification x4) shows a nodular proliferation of small neuroblasts in a background of fibrillary neuropil
. B: High-power histology of the mass (hematoxylin and eosin stain, original magnification x.20) shows small neuroblasts in a background of fibrillary neuropil
Citation: Enriquez et al., "Differing strategies despite shared lineages of motor neurons and glia to achieve robust development of an adult neuropil
in Drosophila," 2018, Neuron 97, 1-17; 7 Feb.