Early in her career, Glinski spent time in neuropsychopharmacology
research supporting discovery of novel treatments for schizophrenia and depression.
The FDA granted Breakthrough Therapy Designation for SEP-363856 based on pivotal, Phase 2 data from Study SEP361-201, which were presented by Sunovion at the 57th annual meeting of the American College of Neuropsychopharmacology
in December 2018, as well as data from Study SEP361-202, a six-month, open-label, safety and tolerability extension study.
The results were published in European Neuropsychopharmacology
The findings were published in the Journal Neuropsychopharmacology
Published in the International Journal of Neuropsychopharmacology
, the preclinical research supports that rapastinel exhibited rapid and sustained antidepressant effects through positive modulation of the NMDA (N-methyl-D-aspartate) receptor and suggests that it may work differently from NMDA receptor antagonists like ketamine and S-ketamine (esketamine).
BARCELONA -- Four potent clinical predictors of treatment-resistant depression have been confirmed in a validation study that showed the four factors collectively have a predictive accuracy of 87%, Alexander Kautzky, MD, reported at the annual congress of the European College of Neuropsychopharmacology
Trevena announced that TRV734 data were featured in a presentation at the annual meeting of the American College of Neuropsychopharmacology
as part of Trevena's ongoing collaboration with the National Institute on Drug Abuse, or NIDA.
The study, published in the journal Neuropsychopharmacology
Reports, explored a small group of young and healthy volunteers with normal work hours and sleep habits to find out if the "hypothalamic-pituitary-adrenal" (HPA) axis responds differently to acute psychological stress according to the time of day.
However, according to a study presented at the American College of Neuropsychopharmacology
, even short periods of sleep deprivation in teens could raise their risk for depression and addiction.
New trials will start However, Prof David director of neuropsychopharmacology
at Imperial, said: "initial findings are exciting."
The research was funded by the National Institute on Alcohol Abuse and Alcoholism and was published in Neuropsychopharmacology
Presentations at symposia at international meetings also have taken place or are ongoing, including a scientific session at the 2016 American Psychiatric Association (APA) annual meeting and another planned for the Presidential Symposium at 2017 APA annual meeting; other presentations are scheduled at the American College of Neuropsychopharmacology
in December 2017 and the European College of Neuropsychopharmacology
in September 2017.