It maintains homeostasis in synaptic neurotransmission
by regulated dopamine uptake.
Bupropion, an antidepressant that enhances noradrenergic and dopaminergic neurotransmission
, has been found effective in children and adults with ADHD.
Dopamine transporter genes assist in the production of proteins that regulate levels of the neurotransmitter dopamine in the brain, while dopamine receptor genes are involved in neurotransmission
Its anxiolytic and antidepressive properties may relate to modulation of central noradrenalin, dopamine, and serotonin, and gamma-aminobutyric acid neurotransmission
and hypothalamic-pituitary-adrenocortical axis activity, said Mr.
The mechanisms underlying the beneficial effect of BC-PS treatment on neuronal connectivity might be explained on the basis of its pharmacological actions on neuronal membranes , neurotransmission
 and/or interaction with NGF .
The Substances part of the volume synthesizes the current understanding of 16 chemicals involved in neurotransmission
, among them acetylcholine, dopamine, histamine, calcitonin gene-related peptide, and peripheral neurogenic stimulators.
in the brain is terminated by the dopamine transporter (DAT), a presynaptic transmembrane protein.
Cyclic changes in ovarian steroids alter serotonin neurotransmission
, Jean Endicott, Ph.D., said at a hearing last year, at which the FDA's psychopharmacologic drugs advisory panel unanimously recommended that fluoxetine be approved for PMDD.
"Genes that in some way are connected with neurotransmission
channels, oxidative stress or the effectiveness of oestrogens seem to be linked to a greater risk for APOEe4 carriers," he explains.
In addition to affecting monoaminergic neurotransmission
, the drug's effect on blood pressure and vascular tone might add to its benefit in migraine, he added.