nicardipine


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ni·car·di·pine

 (nī-kär′də-pēn′)
n.
A calcium channel blocker drug, C26H29N3O6, that acts as a coronary vasodilator and is used in its hydrochloride form to treat hypertension.

[ni(tro)- + car(boxyl) + di(hydro)p(yr)idine, class of drugs to which it belongs.]
References in periodicals archive ?
Objective: This study aimed to compare the effects of labetalol, nicardipine, or hydralazine on time to target blood pressure before alteplase administration in patients with acute ischemic stroke.
Nicardipine of delivering in IV solution, with concentration registered 1 mg / 1 ml and reimbursed in Belgium.
Common drug-drug interactions with ART [19] Class of drug Concomitant medication PIs Anticoagulant: warfarin Anticonvulsants: carbamazepine, phenobarbital, phenytoin Antifungals: ketoconazole, itraconazole, voriconazole Calcium channel blockers: diltiazem, nifedipine, verapamil, amlodipine, nicardipine, isradipine, felodipine, bepridil HMG-CoA reductase inhibitors (statins): lovastatin, simvastatin, atorvastatin Immunosuppressive drugs: cyclosporine, tacrolimus, sirolimus Opioids: methadone PD[E.
Kouoh F, Gressier B, Dine T, et al: Antioxidant effects and anti-elastase activity of the calcium antagonist nicardipine on activated human and rabbit neutrophils-a potential antiatherosclerotic property of calcium antagonists?
Papaverine, calcium antagonists (nimodipine, nicardipine or verapamil) and milrinone (46,47) are effective in reversing cerebral vasospasm to varying extents (48) but repeat treatments are frequently required.
lacidipine, lercanidipine, manidipine, mibefradil nicardipine,
Influence of nicardipine, nimodipine and flunarizine on the anticonvulsant efficacy of antiepileptics against pentylenetetrazol in mice.
INFLUENCE OF NICARDIPINE ON PHARMACODYNAMICS AND PHARMACOKINETICS OF METFORMIN IN RATS/RABBITS 38.
The rapid onset (2-4 minutes), short duration (5-15 minutes), and low potential for drug interactions seen with clevidipine provide advantages over most of the current treatments; however, its benefit over nicardipine remains unclear.
Ginkgo can interact with anticoagulants, anticonvulsants, buspirone, MAO inhibitors, nicardipine, NSAIDs, selective serotonin reuptake inhibitors and diuretics.
Intravenous nicardipine can reduce blood pressure by 15%-20% without impairing blood supply to the brain in hypertensive emergencies, preliminary results from an ongoing case-control study suggest.