Although there were an adequate number of patients who received labetalol to allow for subgroup analyses, the sample size of patients who received nicardipine
or hydralazine was insufficient to provide power for statistical comparison.
All patients with postoperative hypertension were treated with intravenous nicardipine
(first choice) or sodium nitroprusside (second choice).
The mean arterial pressure (MAP) was lowered to between 105 and 125 mmHg by nicardipine
For comparison, the L-type calcium channel blocker nicardipine
(5 or 10 nmol/l) and 17[beta]-estradiol (30 or 100 [micro]mol/l), instead of ScEx, were assayed in a separate series of experiments.
Group 4 medications have evidence indicating no efficacy over placebo: acebutolol, carbamazepine, clomipramine, conazepam, clonidine, indomethacin, nicardipine
, nifedipine, and pindolol.
The CLUE study is important for emergency room physicians because these findings demonstrate that using nicardipine
instead of labetalol is more effective at controlling blood pressure in hypertensive patients," says Frank Peacock, M.
Use of esmolol, nicardipine
or their combination to blunt haemodynamic changes after intubation.
Three levels of SBP reduction in patients suffering ICH were achieved using intravenous nicardipine
within 6 h after bleeding: 170-200, 140-170, or 110-140 mmHg.
has launched nicardipine
hydrochloride injection, indicated for the short-term treatment of hypertension when oral therapy is not feasible or desirable.
Effect of nicardipine
on the hemodynamics of the common carotid artery, peripheral circulation and blood parameters.
The CCBs in these studies were amlodipine, diltiazem, felodipine, isradipine, nicardipine
, nifedipine, nisoldipine, and verapamil.