nifurtimox


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Related to nifurtimox: Eflornithine
Translations

nifurtimox

n nifurtimox m
References in periodicals archive ?
In fact, [PGE.sub.2]production increases significantly in T cruzi-infected macrophages as compared to uninfected macrophages [32] and synergistically enhances the activity of nifurtimox and benznidazole on infected RAW 264.7 cells [23].
cruzi drugs (benznidazole or nifurtimox) with highly active antiretroviral therapy (HAART) to favor immune reconstitution (2,3).
Nifurtimox and benznidazole are the only antichagasic drugs with clinical efficacy, but they are far from optimal because of collateral effects.
After initiation of nifurtimox therapy, his parasitemia rapidly cleared.
Pontes, "Therapy of the chronic phase of the experimental infection by Trypanosoma cruzi with benzonidazole and nifurtimox," Revista da Sociedade Brasileira de Medicina Tropical, vol.
The drugs currently in use against this disease, nifurtimox and benznidazole, present several side effects and have limited efficacy (Kirchhoff, 2003).
After infection was detected, the recipients were treated with nifurtimox provided by the CDC Drug Service, which provides U.S.-licensed physicians with drugs that otherwise would not be available in the United States.
Russo, "Acute Trypanosoma cruzi infection is associated with anemia, thrombocytopenia, leukopenia, and bone marrow hypoplasia: reversal by nifurtimox treatment," Microbes and Infection, vol.
The severe side-effects of benznidazole and nifurtimox, including agranulocytosis, hypersensibility reactions and anorexia, make them poorly tolerated (Almeida and Gazzinelli, 2001).
Mauris et al., "Serological and parasitological response in chronic Chagas patients 3 years after nifurtimox treatment," BMC Infectious Diseases, vol.
The newborn received nifurtimox (10 mg/kg/d for 60 days) without notable adverse effects.
During the last 30 years, the nitroheterocyclic drugs benznidazole (Rochagan[R], Roche) and nifurtimox (Lampit[R], Bayer) are the only choice for treatment of human Chagas disease.