nodes of Ranvier


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node of Ran·vier

 (rän′vyā, rän-vyā′, räN-)
n. pl. nodes of Ranvier
A constriction in the myelin sheath, occurring at varying intervals along the length of a nerve fiber.

[After Louis Antoine Ranvier (1835-1922), French histologist.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nodes of Ranvier - small gaps in the myelin sheath of medullated axons
medullary sheath, myelin sheath - a layer of myelin encasing (and insulating) the axons of medullated nerve fibers
opening, gap - an open or empty space in or between things; "there was a small opening between the trees"; "the explosion made a gap in the wall"
References in periodicals archive ?
The toxin produced by the tick interrupts the sodium flux across axonal membranes in selected locations such as the nodes of Ranvier and nerve terminals.
In the eGFP-[SCs.sup.I] group, cytosolic expression of GFP proteins wrapped P0-expressing compact myelin sheath outwardly and segment-like structures of GFP fluorescence were coincided with P0-lacking sites, suggesting nodes of Ranvier structures.
(1) These domains, including the nodes of Ranvier, the adjoining paranodal regions, the juxtaparanodes, and the internodes, are formed by the interaction between axons and glia in both the central and peripheral nervous systems (CNS and PNS, respectively).
Those domains, called Nodes of Ranvier, become elongated after exposure to loud sound.
The use of myelin significantly saves cellular energy by allowing the saltatory conduction of signals along the axon, where the de-and subsequent repolarization of the axonal membrane is restricted to the nodes of Ranvier [30] (Figure 2).
These gaps, known as nodes of Ranvier, are hot spots for sodium channels--the molecular machinery that is necessary to relay signals along the transmission line.
This occurs along the axon at points called nodes of ranvier, located at gaps in the myelin sheath of peripheral nerves (Hall 2011).
Moore and colleagues demonstrated morphological changes with injection of BTX in rat peroneal nerve including massive swelling of the axon at the nodes of Ranvier with retraction of paranodal myelin, as well as swelling of unmyelinated axons.