sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: role of hydrogen-bonding networks in ligand binding and drug design, J.
Aromatic systems have pretty negative NICS values, antiaromatic systems have strongly positive NICS values, and nonaromatic
cyclic systems should have NICS values close to zero [35,42-44].
where n is the number of bonds taken into account, [alpha] is an empirical constant chosen to give HOMA = 0 for a nonaromatic
system and HOMA =1 for a system with all bonds equal to the optimal value [R.sub.opt], and [R.sub.i] is the individual bond length .
The first-generation retinoids are the naturally occurring nonaromatic
retinoids, including retinol, retinal, isotretinoin (13-cis RA), tretinoin (atRA), and alitretinoin (9-cis RA).
Animals were pair-housed in polycarbonate cages (56 x 33 x 21 cm) with nonaromatic
It was determined that against the background of non-small-cell lung cancer (NSCLC); there is a decrease in the MM level (Table 2); thereat, the revealed regularity is typical for both aromatic and nonaromatic
This is the root cause of metabolic syndrome in patients with increased insulin resistance; (3) testosterone secretion can reduce the circulation of nonaromatic
fatty acids and improve insulin sensitivity.
Cambodia's price for nonaromatic
milled rice is increasingly out of competition with its neighbors.
The naphthyl, phenyl, and phenoxyphenyl isocyanates showed an aromatic absorbance between 260 and 310 nm, but the nonaromatic
adamantyl isocyanate did not absorb in this region (Fig.
Palladium-catalyzed couplings are wonderful, for sure, but it would also be wonderful to be able to form bonds between nonaromatic
carbons just as quickly and easily (a number of people are working on just that problem).
This volume outlines a methodology of regioselective synthesis of aromatic and nonaromatic
carbocyclic and heterocyclic ring systems based mainly on [2+2+2] and [4+2] cycloaddition, and other reactions of acetylenic units, including enediynes and enyne-allenes.