nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium.
The primary outcome was "to evaluate whether regular aspirin or nonaspirin
NSAID use and patterns of use are associated with lower ovarian cancer risk." Analgesic use and data regarding covariates were obtained via self-reported questionnaires.
Intensive use of nonaspirin
nonsteroidal anti-inflammatory drugs (NSAIDs) was associated with improved survival of patients with serous ovarian cancer in a recent population-based study.
medications, such as acetaminophen or ibuprofen.
Use of nonaspirin
nonsteroidal anti-inflammatory drugs during pregnancy and the risk of spontaneous abortion.
Ibuprofen is a propionic acid derivative among NSAID classes and was the first nonaspirin
NSAID to be available over the counter and has become the most commonly used NSAID.
20-HETE has also been shown to be a serious promoter of renal hypertension and to be implicated in an increased risk for renal  and cardiovascular diseases  such as myocardial infarction, hypertension, and heart failure that have also been observed but in a smaller scale with the administration of nonaspirin
traditional NSAIDs [6, 7, 34] (Figure 3(b)).
Huerta-Alvarez, "Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin
nonsteroidal antiinflammatory drugs," Epidemiology, vol.
2012), total caloric intake, physical activity [< 3, 3 to < 9, 9 to < 18, 18 to < 27, or > 27 metabolic equivalent (MET), hours/week], parity (nulliparous, 1, 2-3, or > 4 children), menopausal status and hormone use, nonaspirin
nonsteroidal anti-inflammatory drug use, warfarin use, multivitamin use, hypertension, coronary heart disease (any history of angina, coronary artery stenosis, or myocardial infarction), and rheumatologic disease (any history of systemic lupus erythematosus or rheumatoid arthritis).
The Food and Drug Administration has taken new action to strengthen existing warning labels about the increased risk of heart attack or stroke with the use of prescription and over-the-counter nonaspirin
nonsteroidal anti-inflammatory drugs.
(74) Aspirin, of course, has been in use to prevent inflammation-related cardiovascular problems for many years, and there's evidence that moderate use of both aspirin and nonaspirin
NSAIDs such as ibuprofen may be helpful in preventing certain cancers.
When the data were further analyzed using a Cox proportional hazards regression model, aspirin use was independently associated with lower PCSM (HR 0.43, 95% CI 0.21-0.87) while the use of other nonaspirin
anticoagulants was not significantly associated with PCSM.