noncoding


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noncoding

(ˌnɒnˈkəʊdɪŋ)
adj
(Genetics) genetics relating to any part of DNA that does not code or contain instructions for making protein
References in periodicals archive ?
The role of long noncoding RNA HOTAIR in the acquired multidrug resistance to imatinib in chronic myeloid leukemia cells.
The study is the first to functionally link such mutations to the neurodevelopmental condition and the first clear demonstration of non-inherited, noncoding mutations causing any complex human disease or disorder.
The findings, which appear in the journal Experimental Physiology, tie sleeplessness to changes in the blood levels of micro RNA (miRNA), noncoding molecules that help regulate protein expression.
These results, published December 6, 2018, in Cell Stem Cell, explain how a long noncoding RNA called Morrbid becomes hyperactivated after an acute inflammatory insult.
Citation: Zihao Sun et al., , The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.
Background: Accumulating documents have demonstrated that long noncoding RNAs (lncRNAs) play critical roles in tumorigenesis.
Noncoding RNAs (ncRNAs), including small microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), are responsible for fine regulation of gene expression in stem cells [1].
The reviews broadly cover the topics of DNA methylation, long noncoding RNAs, and single nucleotide polymorphisms, and the original research articles focus on DNA methylation, noncoding centromere RNAs, and mitochondria DNA.
Particularly, noncoding RNAs (including microRNAs, piRNAs, and long noncoding RNAs) received a bulk of attention due to their role as intracellular regulators of gene expression.
Long noncoding RNAs (lncRNAs), a class of RNA segments >200 nucleotides in length, have been considered to be the "noise" of genome transcription owing to their limited protein-coding capacity [7].
With the advent of high-throughput technologies, a wide variety of noncoding RNAs, including microRNAs and long noncoding RNAs (lncRNAs), has been identified in glioma tissues and cell lines, some of which show strong functional indications [9].