Treatment of recalcitrant plaque psoriasis with a humanized nondepleting
antibody to CD4.
In fact, even with a relatively modest reduction in circulating lymphocyte numbers (as using an induction regimen with the nondepleting anti-CD25 monoclonal antibody daclizumab and maintenance therapy with rapamycin and FK506) increased lymphocyte turnover (Ki-67+ cycling T cells) is seen early after transplantation.
In contrast, the frequency of FOXP3+ T cells declines to almost undetectable level after induction with the nondepleting anti-CD25 antibody daclizumab.
Suppression in murine experimental autoimmune thyroiditis: in vivo inhibition of CD4p T cellmediated resistance by a nondepleting
rat CD4 monoclonal antibody.
Principle 7 assumes that resources may be used, but those that are nondepleting
Hence, an investment decision--to develop minerals--punishes a spouse in comparison to a similarly situated spouse who invests in nondepleting
The sensor is nondepleting
, extremely stable, immune to acid gases and will not show false low readings.
Martin et al., "Long-term remission of diabetes in NOD mice is induced by nondepleting
anti-CD4 and anti-CD8 Antibodies," Diabetes, vol.
Franch, "Administration of a nondepleting
anti-CD4 monoclonal antibody (W3/25) prevents adjuvant arthritis, even upon rechallenge: parallel administration of a depleting anti-CD8 monoclonal antibody (OX8) does not modify the effect of W3/25," Cellular Immunology, vol.