Natura's facilities will be dedicated for the manufacture of coconut-oil fractions, coconut-based surfactants and downstream consumer products, which are sustainable, naturally derived, mild and nonirritant
Although Surgicel is a relatively nonirritant
substance and is completely absorbed by the body in most instances, it is a foreign body and should be used as rarely as possible.
Natura's facilities will be used to manufacture coconut oil fractions, coconut-based surfactants, and downstream consumer products which are 'sustainable, naturally derived, mild and nonirritant
First alternative method validated by a retrospective weight-of-evidence approach to replace the draize eye test for the identification of nonirritant
substances for a defined applicability domain.
Although potential benefits and risks of combining irritant pyrethroids with nonirritant
insecticides from complementary classes remain to be satisfactorily assessed, our results suggest that WSEBs might be a potentially scalable delivery format with which to test these hypotheses empirically through large-scale field studies.
It is nonirritant
, noninflammable, and produces bronchodilatation.
The assay allows classification into a nonirritant
, indeterminate and irritant.
The goal of endodontic therapy is to obtain a root canal filling that allows tridimensional sealing of the root canal system, using a nonirritant
material to support periapical healing.
Healing of dermal wounds with macromolecular agents such as natural polymers is preferred to skin substitutes owing to their advantages like biocompatibility, nonirritant
and nontoxic properties and ease and safety of the application on dermis.
are considerably non-toxic or nonirritant
for living cells or tissues.
During the test, recommended nonirritant
doses of the drug should be used.
It has also been postulated that odors can cause health effects by direct irritation or other toxicological effects, by innate or learned aversions at nonirritant
concentrations, and by the presence of a co-pollutant in the odorant mixture (Schiffman & Williams, 2005).