The experiment was performed on Sertoli cell-specific androgen receptor mutant mice, who exhibited higher intratesticular levels of IgG as compared with nonmutant
mice, subsequently resulting into infertility .
In contrast, HDR uses a DNA template, or the nonmutant
homologous chromosome, to achieve a high-fidelity repair and can be used to introduce a precise mutation or insertion by recombination [44-47].
Moreover, KCNJ5-mutated tumor tissue showed a higher number of large clear cells than nonmutant
mice, they found that the protein complex composed of Cbf-beta and the Runx2 transcription factor binds to the Wnt10b promoter to drive Wnt10b expression.
Unfortunately when you run it on this case, it comes up as negative (wild type, normal allele, nonmutant
Other (IDH nonmutant
; "wild-type") infiltrating gliomas never acquire these hallmark IDH mutations and instead follow distinct genetic and behavioral paths of progression.
Due to the unavailability of a segregating population for lipoxygenase assays (MU-Lox-1, MU-Lox-2, and MU-Lox-3), the mutant sources PI 408251 , Jinpumkong-2  and PI 205085, and PI 417458  were grown in a greenhouse and tested, respectively, along with a nonmutant
genotype, cultivar Williams 82 (Table 1).
Detailed in vivo studies have revealed that excessive inflammatory cytokines in MPN originate from both the malignant clone and nonmutant
genotypes did not show this band, maybe mutation was the cause of this event.
They were classified as resistant, mixed, or sensitive based on whether the haplotype represented combinations of resistance related mutations, mutant and nonmutant
forms, or wild type alleles of the gene encoding the drug target in question.
Davies, "Cell-cycle reentry and cell death in transgenic mice expressing nonmutant
human tau isoforms," Journal of Neuroscience, vol.
Mice possessing the mutated gene then are compared with nonmutant
mice for differences in alcohol-related traits.