In turn, oxyR may interact with several DNA-binding proteins, including Dps (DNA-binding protein from starved cells) and H-NS (histone-like nucleoid
structuring protein), causing irreversible DNA condensation and inhibition of DNA-unwinding mechanisms, thus arresting the initiation of DNA replication and initiating the degradation of DNA (Ko et al., 2012).
Woldringh, "Phase separation between nucleoid
and cytoplasm in Escherichia coli as defined by immersive refractometry," Journal of Bacteriology, vol.
reported that, there are 1000 TFAM molecules for one mtDNA in each nucleoid
. TFAM molecules have important regulatory role in biogenesis and stability of mtDNA (65, 66).
The attenuation effect of PCNA on the delay of gap-filling was also detected with the flow cytometry-based nucleoid
Bogenhagen, "Mitochondrial DNA nucleoid
structure," Biochimica et Biophysica Acta, vol.
Observations on the fine structure of mature herpes simplex virus and on the composition of its nucleoid
. J Exp Med.
Mitochondrial DNA transcription regulation and nucleoid
Generally these exist in groups of six to eight genomes bound with proteins in a nucleoid
1B) the functions of targeted ESTs fell into two clusters one comprised protein binding (GO:0051082 GO:0003779 and GO:0005519) another included nucleoid
acid binding activities (GO:0003690 GO:0003677 and GO:0003723).
was centrally located and contained fine DNA fibrils.
Reyes et al., "The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid
organization," Journal of Cell Biology, vol.
In the second, partial protein depletion from chromatin results in a characteristic pattern of DNA loops, spreading around a nucleoid
of DNA that remains attached to protein residues (Fernandez et al.