nucleoside


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.

nu·cle·o·side

 (no͞o′klē-ə-sīd′, nyo͞o′-)
n.
Any of various compounds, such as adenosine or guanosine, that consist of a sugar, usually ribose or deoxyribose, linked to a purine or pyrimidine base. Nucleosides are constituents of the nucleotides that make up nucleic acids.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

nucleoside

(ˈnjuːklɪəˌsaɪd)
n
(Biochemistry) biochem a compound containing a purine or pyrimidine base linked to a sugar (usually ribose or deoxyribose)
[C20: from nucleo- + -ose2 + -ide]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

nu•cle•o•side

(ˈnu kli əˌsaɪd, ˈnyu-)

n.
any of the class of compounds derived by the hydrolysis of nucleic acids or nucleotides, consisting typically of deoxyribose or ribose combined with adenine, guanine, cytosine, uracil, or thymine.
[< German Nucleosid (1909)]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nucleoside - a glycoside formed by partial hydrolysis of a nucleic acid
adenosine - (biochemistry) a nucleoside that is a structural component of nucleic acids; it is present in all living cells in a combined form as a constituent of DNA and RNA and ADP and ATP and AMP
glycoside - a group of compounds derived from monosaccharides
inosine - a nucleoside that is formed by the deamination of adenosine; used in kidney transplantation to provide a temporary source of sugar
deoxyadenosine - a nucleoside component of DNA; composed of adenosine and deoxyribose
cytidine, deoxycytidine - a nucleoside component of DNA; composed of cytosine and deoxyribose
deoxyguanosine, guanosine - a nucleoside component of DNA; composed of guanine and deoxyribose
deoxythymidine, thymidine - a nucleoside component of DNA; composed of thymine and deoxyribose
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
nucléoside
References in periodicals archive ?
A DNA molecule is initially composed of a string of nucleoside monophosphates (NMPs) held together by covalent bonds between the 3'--OH of one subunit, and the innermost (alpha) phosphate group on the 5' end of another NMP (the other two phosphate groups are released in the joining reaction).
The transporter molecule, called a concentrative nucleoside transporter, works by moving nucleosides, the building blocks of DNA and RNA, from the outside to the inside of cells.
Nucleoside analogues###Ribavirin###Viramidine (Taribavirin)
There are no clinically significant pharmacokinetic interactions between nucleoside reverse transcriptase inhibitors (NRTIs) and rifampicin-based TB treatment.
The hENT1 companion diagnostic is being developed to identify pancreatic cancer patients with low-level tumour expression of the human equilibrative nucleoside transporter 1 (hENT1) protein.
BOSTON -- Recent use of the nucleoside analogues abacavir and didanosine is associated with a significantly increased risk of myocardial infarction in HIV-infected individuals, whereas treatment with the thymidine analogues appears to convey no such risk, according to findings presented at the 15th Conference on Retroviruses and Opportunistic Infections.
The company also has a comprehensive HCV discovery effort, comprised of a next-generation nucleoside polymerase inhibitor program, including IDX102 and IDX184, which are currently being evaluated in advanced preclinical testing, and HCV non-nucleoside polymerase inhibitor and HCV protease inhibitor programs.
nucleoside analogue reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), RNA polymerase inhibitors, integrase inhibitors.
Ed4T, which was developed by Yale University, Kagoshima University and Showa University, is a nucleoside reverse transcriptase inhibitor with enhanced anti-HIV-1 activity.
These medications used in combination with other antiretrovirals, namely the nucleoside and non-nucleoside reverse transcriptase inhibitors, truly changed HIV into a more chronic illness.
The company is developing Viramidine, a nucleoside (guanosine) analog, in oral form for administration in combination with pegylated interferon for the treatment of chronic hepatitis C in treatment-naive patients.
2000 New medication Trizivir combines three nucleoside analogs into one pill

Full browser ?