nucleotidase


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nu·cle·o·tid·ase

 (no͞o′klē-ə-tī′dās, -dāz, nyo͞o′-)
n.
An enzyme that catalyzes the hydrolysis of a nucleotide to a nucleoside and phosphoric acid.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

nucleotidase

(ˌnjuːklɪəˈtaɪdeɪs; ˌnjuːklɪəˈtaɪdeɪz)
n
(Biochemistry) biochem a biochemical catalyst that facilitates the process of hydrolyzing or splitting a nucleotide and turning it into a phosphate and a nucleoside
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
DNA is extremely unstable inside and outside the cell and is likely to be degraded by nucleotidase. Stably transferring exogenous gene into target cell for gene therapy depends on the gene transfer system [40], and stable and effective gene vector is of importance to gene therapy [41].
Gutterman et al., "Ecto-5'nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase," Arteriosclerosis, Thrombosis, and Vascular Biology, vol.
Differentials include haemoglobinopathies (thalassemias), lead or arsenic poisoning, unstable haemoglobins, severe infections, sideroblastic anaemia, megaloblastic anaemia and a rare inherited condition, pyrimidine 5' nucleotidase deficiency [14,22,42].
Clinical laboratory tests can show biliary obstruction, with elevated bilirubin, alkaline phosphatase, 50 nucleotidase, and gamma-glutamyl transpeptidase, especially with involvement of the common bile duct.
Effect of Scutia buxifolia Reissek in nucleotidase activities and inhibition of platelet aggregation.
The import of exogenous nucleotides usually precedes their dephosphorylation, and a membrane-associated protein with similarity to bacterial 5' nucleotidase was recently show to be expressed by M.
Anticoagulant effect of Naja naja venom 5' nucleotidase: demonstration through the use of novel specificinhibitor vanillic acid.
M., 1970, "A specific colorimetric 5'nucleotidase assay utilizing the Berthelot reaction,".
I suggest MICRONUCLEATE, NUCLEOSIDASE and NUCLEOTIDASE, all in Websters 3d New International."
Inosine monophosphate may then be converted to inosine by 5' nucleotidase, which, in turn, is converted to hypoxanthine by the action of nucleoside phosphorylase.