nude mouse

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nude′ mouse′

a hairless mutant laboratory-bred mouse having an immune system deficiency and able to accept grafts of foreign tissue.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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Noun1.nude mouse - a mouse with a genetic defect that prevents them from growing hair and also prevents them from immunologically rejecting human cells and tissues; widely used in preclinical trials
mouse - any of numerous small rodents typically resembling diminutive rats having pointed snouts and small ears on elongated bodies with slender usually hairless tails
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To evaluate the effect of silencing XB130 on tumorigenesis in vitro , we established a nude mouse model of tumor formation and injected the shA and NC groups subcutaneously.
Pluristem Therapeutics announced the publication of a peer-reviewed article in the journal Scientific Reports, from the publisher of Nature, titled, "Human Placental-Derived Adherent Stromal Cells Co-Induced with TNF-alpha and IFN-gamma Inhibit Triple-Negative Breast Cancer in Nude Mouse Xenograft Models." The article is based on studies which examined the effect of PLX cells that had been induced with tumor necrosis factor alpha and interferon-gamma, on the proliferation of over 50 lines of human cancerous cells.
CD20 and CD5 nanoprobes are, respectively, injected into nude mouse models via the caudal vein to observe in vivo upconversion fluorescence imaging of both nanoprobes in the mouse models.
Murakami et al., "Tumortargeting Salmonella typhimurium A1-R sensitizes melanoma with a BRAF-V600E mutation to vemurafenib in a patient-derived orthotopic xenograft (PDOX) nude mouse model," Journal of Cellular Biochemistry, vol.
The 21 orthotopic tumor models were established by injecting 2 x [10.sup.6] HCC-LM3-fLuc tumor cells into the liver of each BALB/c nude mouse. The mice were randomly separated into 3 groups each consisting of 7 mice.
Angiogenic responses of EPCs of each patient were quantitatively assessed by directed in vivo angiogenesis assay (DIVAA) in a nude mouse according to the protocol of the manufacturer (Trevigen, MD, USA).
in cultured skin fibroblasts and nude mouse skin indicated that daidzein treatment appears to increase skin collagen production and suppress collagen degradation.
Treatment of pancreatic cancer in a nude mouse model using high-intensity focused ultrasound.
To detect the effect of SNHG12 knockdown in vivo, a nude mouse xenograft model of HT29 cells was established.
Hoffman, "Nude mouse metastatic models of human stomach cancer constructed using orthotopic implantation of histologically intact tissue," Cancer Research, vol.
In this study, we investigate the effects of SLPE on the cell cycle and its ability to induce apoptosis in a xenograft tumor nude mouse model.