obtund - reduce the edge or violence of; "obtunded reflexes"
blunt, deaden - make less lively, intense, or vigorous; impair in vigor, force, activity, or sensation; "Terror blunted her feelings"; "deaden a sound"
Ischemic complications should be avoided by choosing agents that are less likely to make sudden and important changes in hemodynamics, less capble to obtund sympathetic response to tracheal intubation and surgical stimulation, and have a negative effect on the nutrition of tissues.
It is necessary to obtund the heart rate response during intubation, especially in patients with mitral stenosis for life-threatening complications, and esmolol was found to be beneficial in our study without any untoward responses.
Furthermore, as every individual has a distinct, idiosyncratically organized peripheral personality structure it can be seen that collective identification with ADP does not obtund one's individuality.
Extreme care is to be undertaken to obtund the hypertensive response during induction-intubation, as this has been a significant past cause of maternal mortality (61).
While several problems can arise during anaesthesia in patients with pre-eclampsia/eclampsia, those described in the Saving Mothers reports include failure to obtund the intubation response and severe hypertension after administration of ergotamine.
Anaesthesiologists have been trying to obtund these untoward reflexes by the use of various measures such as:-Curtailing or shortening the duration of laryngoscopy to less than 15 seconds.