oestrone


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Related to oestrone: estradiol

oestrone

(ˈiːstrəʊn; ˈɛstrəʊn) or

estrone

n
(Biochemistry) a weak oestrogenic hormone secreted by the mammalian ovary and having the same medical uses as oestradiol. Formula: C18H22O2
[C20: from oestr(us) + -one]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.oestrone - a naturally occurring weak estrogenic hormone secreted by the mammalian ovary; synthesized (trade name Estronol) and used to treat estrogen deficiency
estrogen, oestrogen - a general term for female steroid sex hormones that are secreted by the ovary and responsible for typical female sexual characteristics
ketosteroid - a steroid containing a ketone group
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Adverse reproductive effects in male fathead minnows (Pimephales promelas) exposed to environmentally relevant concentrations of the natural estrogens, oestradiol, and oestrone. Aquatic Toxicology, 42: 243-253.
[93-95], which indicated the modulatory effect of steroid hormones, [P.sub.4], oestrone, and [E.sub.2], as well as prostaglandins: [E.sub.2] and [F.sub.2[alpha]] on the adiponectin system expression in the porcine pregnant uterus.
The greater the obesity, the more will be the peripheral aromatisation of androgens to oestrogens especially oestrone. The high concentration of oestrone sensitises the pituitary to secrete excessive androstenedione, which perpetuates the vicious cycle of androgen to oestrone.
Androstenedione and testosterone are converted to oestrone in adipose tissue and it is likely that this pathway underlies the increase in exposure of the breasts to oestrogen in the obese.
The main source of oestrogens would be the peripheral aromatisation of androgens into oestrone, which is a weak oestrogen compared with ovarian-derived oestradiol.
Postmenopausal concentrations of plasma oestradiol, estrone, FSH, and LH and of total urinary oestrone after a single sublingual dose of estradiol 17-11.
oestradiol and oestrone), androstanes ([C.sub.19]) (e.g.