ofloxacin


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o·flox·a·cin

 (ə-flŏk′sə-sĭn)
n.
An antibiotic of the fluoroquinolone class, C18H20FN3O4, used to treat various infections, especially of the urinary tract, urethra, and skin.

[Probably o(xy)- (from its oxygen-containing pyridine ring) + -floxacin, fluoroquinolone suff.; see ciprofloxacin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Translations

ofloxacin

n ofloxacino, ofloxacina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive ?
Association of mutation patterns in gyrA/B genes and ofloxacin resistance levels in Mycobacterium tuberculosis isolates from East China in 2009.
In the present study compatibility of ofloxacin was assessed with some commonly used excipients.
However, studies carried out in India have reported that only 11.7 (4) and 45 per cent5 of ofloxacin resistant M.
The researchers found that the phage increased the ability of the antibiotic ofloxacin to kill E.
We have, therefore, confiscated them and the Ministry of Health was notified for further action," he said.The medicines included Chinese versions of Cefradine capsules, Amoxicillyn capsules, Azhithromycin Dispersible tablets, Cefalexin tablets, Ofloxacin tablets, and several other health supplements.
Medications on the list include the fluoroquinolones ciprofloxacin (Cipro), levofloxacin (Levaquin), moxifloxacin (Aveiox), norfloxacin (Noroxin), and ofloxacin (Floxin).
The fluoroquinolone drugs that will carry the new labeling include ciprofloxacin (marketed as Cipro and generic ciprofloxacin), ciprofloxacin extended release (Cipro XR and proQuin XR), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), and ofloxacin (Floxin and generic ofloxacin).
Many of these multidrug-resistant staphylococci are resistant, by laboratory definitions, to fluoroquinolones such as ciprofloxacin, ofloxacin, levofloxacin, and moxifloxacin.
SUMMARY: Ofloxacin presents an ample spectrum of antimicrobial action, including combating Mycobacterium leprae, and is currently employed as a substitute when the use of rifampicin is impossible.
Quinolones (ciprofloxacin, ofloxacin) are effective and probably compatible with breastfeeding; however, their use has not been recommended by many investigators based on arthropathy in animal studies (SOR: C, based on extrapolation from case series and disease-oriented outcomes).
On page 59, under "Recommended Regimen A," the daily dosage for Ofloxacin was incorrect.