ofloxacin

Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.

o·flox·a·cin

(ə-flŏk′sə-sĭn)

An antibiotic of the fluoroquinolone class, C₁₈H₂₀FN₃O₄, used to treat various infections, especially of the urinary tract, urethra, and skin.

[Probably o(xy)- (from its oxygen-containing pyridine ring) + -floxacin, fluoroquinolone suff.; see ciprofloxacin.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Translations

ofloxacin

n ofloxacino, ofloxacina

Mentioned in ?

levofloxacin

References in periodicals archive ?

Association of mutation patterns in gyrA/B genes and ofloxacin resistance levels in Mycobacterium tuberculosis isolates from East China in 2009.

Characterization of gyrA and gyrB mutations and fluoroquinolone resistance in Mycobacterium tuberculosis clinical isolates from Hubei Province, China

In the present study compatibility of ofloxacin was assessed with some commonly used excipients.

Influence of sample preparation method on isothermal studies during compatibility screening of ofloxacin; correlation with DSC data

However, studies carried out in India have reported that only 11.7 (4) and 45 per cent5 of ofloxacin resistant M.

Effect of efflux pump inhibitors on drug susceptibility of ofloxacin resistant Mycobacterium tuberculosis isolates

The researchers found that the phage increased the ability of the antibiotic ofloxacin to kill E.

Engineered viruses may help fight drug-resistant superbugs

We have, therefore, confiscated them and the Ministry of Health was notified for further action," he said.The medicines included Chinese versions of Cefradine capsules, Amoxicillyn capsules, Azhithromycin Dispersible tablets, Cefalexin tablets, Ofloxacin tablets, and several other health supplements.

Chinese drugs seized

Medications on the list include the fluoroquinolones ciprofloxacin (Cipro), levofloxacin (Levaquin), moxifloxacin (Aveiox), norfloxacin (Noroxin), and ofloxacin (Floxin).

FDA warns that some antibiotics can cause tendon ruptures, tendonitis

The fluoroquinolone drugs that will carry the new labeling include ciprofloxacin (marketed as Cipro and generic ciprofloxacin), ciprofloxacin extended release (Cipro XR and proQuin XR), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), and ofloxacin (Floxin and generic ofloxacin).

Tendinitis warning is added to fluoroquinolones

Many of these multidrug-resistant staphylococci are resistant, by laboratory definitions, to fluoroquinolones such as ciprofloxacin, ofloxacin, levofloxacin, and moxifloxacin.

Bacterial resistance to quinolone otic drops is nearly zero

SUMMARY: Ofloxacin presents an ample spectrum of antimicrobial action, including combating Mycobacterium leprae, and is currently employed as a substitute when the use of rifampicin is impossible.

Study of the nuclear volume of testicular cells of rats receiving ofloxacin through lactation/ Estudio del volumen nuclear de celulas testiculares de ratas que recibieron ofloxacin durante la lactancia

(Weston, Ontario) and said a Daiichi patent on ofloxacin otic, the chemical name for the drug, was invalid, reversing a lowercourt ruling.

Daiichi Sankyo Co, Japan's second-largest drugmaker, lost an appeals court ruling and could face generic competition in the US to its Floxin Otic, a medicine for treating ear infections, including swimmer's ear

Quinolones (ciprofloxacin, ofloxacin) are effective and probably compatible with breastfeeding; however, their use has not been recommended by many investigators based on arthropathy in animal studies (SOR: C, based on extrapolation from case series and disease-oriented outcomes).

Which UTI therapies are safe and effective during breastfeeding?

On page 59, under "Recommended Regimen A," the daily dosage for Ofloxacin was incorrect.