oncolysis


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oncolysis

(ɒŋˈkɒlɪsɪs)
n
(Biology) the destruction of tumours
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
Translations

on·col·y·sis

n. oncólisis, destrucción de las células de un tumor.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
These include antiangiogenic agents, immunotherapy, bacterial agents, viral oncolysis, targeting of cyclic-dependent kinases and tyrosine kinase receptors, antisense approaches, gene therapy and combination of various methods.
It has been engineered to combine the killing of cancer cells (oncolysis), the production of 5-FU, a widely used chemotherapeutic agent, in the tumor site, and the eliciting of an immune response against tumor cells.
It is a next generation oncolytic immunotherapy designed to induce the breakdown of cancer cells (oncolysis) and allow the local production of chemotherapy (5-FU) in the tumour.
Through strong inhibition of cancer initiating cells (CIC's) and a myriad of other immuno-suppressive forces in the tumor micro-environment, there was improved tumour free survival when compared to oncolysis alone in a xenograft model.
"The proinflammatory effects of viral oncolysis may stem from its attraction and activation of natural killer cells, which through the production of chemokines in the tumour, control the levels of stimulatory dendritic cells.
Macrophages can either support oncolytic virus therapy through proinflammatory stimulation of the antitumor response at the cost of hindering direct oncolysis or through immunosuppressive protection of virus replication at the cost of hindering the antitumor immune response [79].
Wares, "Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics," Mathematical Biosciences and Engineering, vol.
The oHSV loaded stem cells are ultimately killed by oHSV mediated oncolysis. This rids the brain of the engineered cells, making the process safer.
Curiel, "Efficient oncolysis by a replicating adenovirus (ad) in vivo is critically dependent on tumor expression of primary Ad receptors," Cancer Research, vol.
OV-mediated oncolysis not only leads to tumor regression but also provides important immune responses.
Garcia-Garcia et al., "Adenoviruses induce autophagy to promote virus replication and oncolysis," Virology, vol.