one-two punch


Also found in: Idioms.

one-two punch

n.
1. A combination of two blows delivered in rapid succession in boxing, especially a left lead followed by a right cross.
2. Informal An especially forceful or effective combination or sequence of two things.
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Washington, June 6 ( ANI ): Scientists are reporting development and successful lab tests on the first potential drug to pack a lethal one-two punch against melanoma skin cancer cells.
Bolton joins a growing number of communities that are looking at its budget and realizing that Mother Nature's one-two punch has scored a knock-out (see story, page 1).
But staggering from 2000's bruising six-month commercial strike, Propaganda ultimately succumbed to a nasty one-two punch: The blow of the Internet bust was followed quickly by a dearth of TV ads in a softening real-world economy and the Sept.
Forget about a mere one-two punch. When Hurricanes Dennis, Floyd, and Irene pummeled North Carolina in the fall of 1999, they delivered a three-punch combination that for years to come may disturb coastal ecosystems there and disrupt fishing in the Atlantic Ocean.
Ian Sanggalang and Paul Lee provided Magnolia's one-two punch while Mark Barroca, Aldrech Ramos, Jio Jalalon and chimed in on the defensive effort.
The Hotshots' one-two punch in big man Ian Sangalang and guard Paul Lee, bolstered by import Vernon Macklin, powered the team past the clutches of the Batang Pier in the final five minutes of the game.
The Rice team suggests maximizing the benefits of synthetic AMPs by using them in drug cocktails that act like a one-two punch for either bacteria or cancer.
The usual holiday rush is simply not job one in a season that has seen a one-two punch from the economy and the weather.
This one-two punch awakens a potent cancer-fighting gene called RAR-beta-2, which is found on chromosome 3, say the scientists.
Although the industry gushes over his one-two punch of "The Practice" and "Ally McBeal" David E.
Mike Harris and Chris Banchero formed a lethal one-two punch to power Alaska past Blackwater, 116-109, in the 2018 PBA Governors' Cup Sunday night at Smart Araneta Coliseum.
The 10th-ranked Australians banked on the one-two punch of Cameron Gliddon and Mitchell Creek to pull away in the third and to add to the Filipinos' free throw struggles.