onycholysis


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on·y·chol·y·sis

 (ŏn′ĭ-kŏl′ĭ-sĭs)
n.
The separation or loosening of a fingernail or toenail from its nail bed.

[New Latin : Greek onux, onukh-, nail, claw; see onyx + -lysis.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.onycholysis - separation of a nail from its normal attachment to the nail bed
onychosis - any disease or disorder of the nails
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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Of note, there are subsets of lichen striatus: Hypopigmented lichen striatus with minimal papules has been termed "lichen striatus albus." Nail lichen striatus may present as onycholysis or fissuring of nails, present as an isolated finding, or more commonly in association with concurrent affected skin.
Of note, there are subsets of lichen striatus: Hypopigmented lichen striatus with minimal papules has been termed "lichen striatus albus." Nail lichen striatus may present as onycholysis or Assuring of nails, present as an isolated finding, or more commonly in association with concurrent affected skin.
The main dermatologic side effects of FOLFOX therapy are pruritus, nail discoloration, onycholysis, alopecia, and hand-foot syndrome (25).
Acute bullous dermatosis and onycholysis due to high-dose methotrexate and leucovorin calcium.
Other adverse drug reactions were acneiform drug eruptions, DRESS, drug-induced hyperpigmentation, drug-induced onycholysis, and SJS.
Symptoms of iodine-induced hyperthyroidism may include resting tremor, enlarged thyroid, hair loss, arrhythmia, onycholysis, gyneocomastia, proptosis, hyperreflexia, heat intolerance, irritability, insomnia, weight loss, increased appetite, diarrhea, amenorrhea, decreased libido, and photophobia.
Regarding the location of the nail pathology, the clinical presentation is different; pitting, leukonychia, red spots in the lunula, nail plate crumbling, beaus lines, and trachyonychia are signs of nail matrix involvement and onycholysis, oil drop discoloration or salmon patch, subungual hyperkeratosis, and splinter hemorrhage indicate nail bed disease.
The patient also noticed onycholysis in both his hands and feet (Figure 1), followed by hyperpigmentation of his hands (Figure 2), soles of his feet and legs, and abdomen.
The following exclusion criteria were employed: any nail lesions that could be definitely diagnosed as onychomycosis, onycholysis, twenty-nail dystrophy, subungual hemorrhage, or nail disease caused by lichen planus or psoriasis.
The patient presented with oil drops on almost all fingernails and on nails of both big toes together with mild distal onycholysis. Furthermore, swelling with redness of the distal interphalangeal joints (DIP) of the right index and left little finger was evident (Figure 1).
The following nail changes were recorded: pitting, crumbling, onycholysis, oil drop, subungual hyperkeratosis, and splinter hemorrhage.
The analysis of the role of selected proinflammatory and angiogenic cytokines in SpA patients [14, 15, 32, 33] showed higher levels of IL-23 in ankylosing spondylitis in comparison with the controls and revealed the association with selected clinical characteristics such as psoriatic onycholysis and the use of nonsteroid anti-inflammatory drugs [14, 15].