opsonin


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to opsonin: opsonization, Cytokines

op·so·nin

 (ŏp′sə-nĭn)
n.
A substance, such as an antibody or complement protein, that binds to a bacterium or other pathogen and causes it to become more susceptible to the action of phagocytes.

[Latin opsōnāre, to buy provisions (from Greek opsōnein, from opson, condiment, delicacy; see epi in Indo-European roots) + -in.]

opsonin

(ˈɒpsənɪn)
n
(Biochemistry) a constituent of blood serum that renders invading bacteria more susceptible to ingestion by phagocytes in the serum
[C20: from Greek opsōnion victuals]
opsonic adj

op•so•nin

(ˈɒp sə nɪn)

n.
any of several constituents of blood serum, as an antibody or complement, that make invading microorganisms more susceptible to destruction by phagocytes.
[1900–05; < Latin opsōn(ium) victuals]
op•son•ic (ɒpˈsɒn ɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.opsonin - an antibody in blood serum that attaches to invading microorganisms and other antigens to make them more susceptible to the action of phagocytes
blood serum, serum - an amber, watery fluid, rich in proteins, that separates out when blood coagulates
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
Translations
opsonina

op·so·nin

n. opsonina, anticuerpo que al combinarse con un antígeno hace que éste sea más suceptible a los fagocitos.
References in periodicals archive ?
MBL works as opsonin and initiates lectin complement activation pathway [20].
Steric PEG block chains on the surface of micelles can decrease the opsonin protein binding in vivo and therefore block the capture by the reticuloendothelial system (RES) efficiently [15].
Lysozyme is an important component in the nonspecific humoral immune which possess both bactericidal as well as opsonin effects that activate the complement system and phagocytes to prevent infection and disease.
Patients with liver cirrhosis suffer from immunosuppression due to multiple reasons such as decreased phagocytic activity of neutrophilic granulocytes and the mononuclear phagocytic system deteriorated humoral immunity and decreased opsonin activity of ascitic fluid16.
To rapidly cleanse the blood of pathogens, the patient's blood is mixed with magnetic nanobeads coated with a genetically engineered version of a human blood 'opsonin' protein that binds to a wide variety of bacteria, fungi, viruses, parasites, and toxins.
Importantly, in the past years, synaptic pruning was found to be determined by the microglial chemokine receptor C[X.sub.3]CR1 and the classical complement cascade, including, most notably, signaling between the microglial complement receptor 3 (CR3) and the neuronal opsonin C3 [21, 28].
Taira et al., "A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin," Journal of Biological Chemistry, vol.
The bioactivity of lectin may appear to function as a pattern recognition protein specific for Gram-negative and acid-fast bacteria through its interaction with Lipopolysaccharide (LPS), and also as an opsonin to increase the efficiency of hemocyte phagocytosis.
Another new finding was that when CRP was allowed to interact with human LOX-1 in vitro, complement was activated (as measured by the generation of the opsonin C3d).