We use precisely this light in our optoacoustic
imaging technique for tumor diagnosis.
The team of researchers demonstrated a relationship between the metabolic activation of the tissue and changes in oxygenated and deoxygenated hemoglobin (red blood pigment), measured by means of multispectral optoacoustic
3D visualization of changes in physiological properties of mouse tissues from live to postmortem," in Proceedings of the Photons Plus Ultrasound: Imaging and Sensing 2012, USA, January 2012.
Ntziachristos, "Mesoscopic and macroscopic optoacoustic
imaging of cancer," Cancer Research, vol.
Shcherbakov, "Investigation of the [H.sub.2]O line broadening using an optoacoustic
laser spectrometer in the range of 12411-12421 [cm.sup.-1]," Russian Physical Journal, vol.
Yoh, "Reduced graphene oxide coated polydimethylsiloxane film as an optoacoustic
transmitter for high pressure and high frequency ultrasound generation," Applied Physics Letters, vol.
The final processing outcome is termed an optoacoustic
value (OAV), which is an arbitrary value.
Fysarakis, "Insect biometrics: optoacoustic
signal processing and its applications to remote monitoring of McPhail type traps," PLoS One, vol.
Oraevsky, "Melanin nanoparticles as a novel contrast agent for optoacoustic
tomography," Photoacoustics, vol.
Razansky, Simultaneous visualization of tumour oxygenation, neovascularization and contrast agent perfusion by real-time three-dimensional optoacoustic
tomography, European Radiology, 26, 1843-1851 (2016).
Razansky, "High-frame rate four dimensional optoacoustic
tomography enables visualization of cardiovascular dynamics and mouse heart perfusion," Scientific Reports, vol.
Among the topics are introduction to light scattering by biological objects, coherence phenomena and statistical properties of multiply scattered light, time-resolved imaging in diffuse media, monitoring brain activity with near-infrared spectroscopy, signal quantification and localization in tissue with near-infrared spectroscopy, and measuring optical fluence distribution and optical properties of tissues using time-resolved profiles of optoacoustic