ornithine


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or·ni·thine

 (ôr′nə-thēn′)
n.
An amino acid, C5H12N2O2, not found in proteins, formed by hydrolyzing arginine and important in the formation of urea.

[ornith(uric acid), an acid found in birds' urine (ornith(o)- + uric acid) + -ine.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ornithine

(ˈɔːnɪˌθiːn)
n
(Biochemistry) an amino acid produced from arginine by hydrolysis: involved in the formation of urea in the liver; diaminopentanoic acid. Formula: NH2(CH2)3CHNH2COOH
[C19: from ornithuric (acid) secreted in the urine of birds, from ornitho- + uric]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

or•ni•thine

(ˈɔr nəˌθin)

n.
an amino acid, H2N(CH2)3CH(NH2)COOH, obtained by the hydrolysis of arginine and occurring as an intermediate compound in the urea cycle of mammals.
[1880–85; ornith(uric acid), secreted by birds + -ine2]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ornithine - an amino acid that does not occur in proteins but is important in the formation of urea
amino acid, aminoalkanoic acid - organic compounds containing an amino group and a carboxylic acid group; "proteins are composed of various proportions of about 20 common amino acids"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
Ornithin
ornithine
ornityna

or·ni·thine

n. ornitina, aminoácido que aunque no está presente en las proteínas desempeña un papel importante en el ciclo de la urea.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
Arcturus' diverse pipeline of RNA therapeutics includes programs to potentially treat Ornithine Transcarbamylase (OTC) Deficiency, Cystic Fibrosis, Glycogen Storage Disease Type 3, Hepatitis B, and non-alcoholic steatohepatitis (NASH).
At just nine months old, Ava was diagnosed with Ornithine Transcarbamylase (OTC) deficiency, which means her body builds up dangerous levels of ammonia and can lead to brain damage.
(NYSE:MRK)'s Keytruda in ornithine transcarbamylase deficiency.
Food and Drug Administration to proceed with a single-ascending dose Phase 1/2 clinical trial of MRT5201 in adult patients with ornithine transcarbamylase deficiency.
Plasma amino acid examination (high-performance liquid chromatography) on 2 occasions revealed increased arginine at 309 and 377 (reference interval, 15-160) ^mol/L and ornithine at 210 and 361 (30-150) ^mol/L, while all other amino acids including citrulline and glutamine were within reference limits.
Ornithine transcarbamylase deficiency (OTC) is the most common urea cycle disorder with an estimated prevalence of 1 per 80000 births.
It may also contain an amino acid, ornithine, and some selenium, an antioxidant.
The first group consisted of seven amino acids (glycine, ornithine, alanine, leucine/isoleucine, tyrosine, aspartic acid, and glutamic acid) that drop sharply from the zerotime point collected shortly after birth to the median of the 6-12 month age group.
The average intra-assay coefficient of variation was 4.3% for histidine, 4.6% for ornithine, and 4.6% for phenylalanine.
is a clinical stage biopharmaceutical company focussed on the development and commercialisation of OCR-002 (ornithine phenylacetate) in both intravenous and oral formulations.
DTX301 is intended for the treatment of ornithine transcarbamylase deficiency.
Ornithine transcarbamylase (OTC) deficiency (also referred to as ornithine carbamoyltransferase deficiency) is an Xlinked proximal urea cycle disorder that results in a spectrum of severe neonatal-onset disease in boys, rarely in girls, and a milder adult-onset presentation.