orthology


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Related to orthology: Paralogy

orthology

the art of correct grammar and correct use of words. — orthologer, orthologian, n. — orthological, adj.
See also: Language
-Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved.
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To identify transcripts encoding proteins potentially relevant to salt stress, we compared the six-frame conceptual translation products of nucleotide query sequence (both strands) against five databases including KEGG (Kyoto Encyclopedia of Genes and Genomes) Orthology database (Pacific oyster Crassostrea gigas database); DBGET Orthology database (sea hare Applysia californica database); Gene Ontology Consortium V.20150407; National Center for Biotechnology Information non-redundant (nr) protein; and UniProtKB, using BLASTX v.2.4.0 (National Center for Biotechnology Information, Bethesda, MD) with an e-value of [1e.sup.-5].
The data generated by Arabidopsis model studies reveal that similar processes exist in other plants because of gene homology and orthology (Bauer et al., 2004).
Tenants in the space include a two-story Walgreens store, a North Memorial medical clinic and an Orthology sports medicine clinic, United spokeswoman Sheila Thelemann said in an email statement.
Forslund et al., "egg-NOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences," Nucleic Acids Research, vol.
Gene Set Analysis (GSA) showed significant expression of genes in five and nine KEGG orthology (KO) pathways in BR7 and BR21, respectively (Figure 2).
Wei, "Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary," Bioinformatics, vol.
Using the Kyoto Encyclopedia of Genes and Genomes orthology database, each sequence can be directly mapped to a Kyoto Encyclopedia of Genes and Genomes orthology representative sequence; the sum of sequences belonging to a particular pathway can then be computed (32, 33).
Discovering quantitative trait genes (QTGs) in mouse reference populations that affect toxicity susceptibility have the potential to be translated into humans, especially where there is high sequence homology (or reasonable orthology of the resultant protein) between mouse and human species for the QTG of interest.
According to the classification of the Kyoto Encyclopedia of Genes and Genomes (KEGG) Orthology in the KEGG databases (http://www.genome.jp/kegg/), the majority of the putative targets of these miRNAs were involved in the CML pathway.
Ostlund, "InParanoid 8: Orthology analysis between 273 proteomes, mostly eukaryotic," Nucleic Acids Research, vol.
Predicted protein-protein interactions are derived from multiple sources including known experimental interactions (coexpression, experiments), genome functional pathway knowledge from manually curated databases (databases), automated text-mining searches (text-mining), shared gene neighborhood locations across multiple genomes (neighborhood), and interactions observed in one organism and systematically transferred to other organisms, via precomputed orthology relations (cooccurrence and gene fusion).