In Xofluza-treated participants, 46.1% experienced at least one treatment-emergent AE compared to 53.4% in the oseltamivir
Phase III MINISTONE-2 data are consistent with known safety profile of Xofluza (baloxavir marboxil) in children and show comparable efficacy to oseltamivir
In 2006, former GSIS president and general manager Winston Garcia entered into an agreement with pharmaceutical company Unilab to buy Oseltamivir
, a medicine used to treat avian flu.
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Baloxavir better reduced viral load at day 2, compared with oseltamivir
and placebo, but there was a similar alleviation of symptoms between both groups.
The approval was based on results from the phase III Capstone-1 study of a single-dose of Xofluza compared with placebo or oseltamivir
75mg, twice daily for five days, and also results based on a placebo-controlled phase II study.
The time to symptom alleviation was similar for baloxavir and oseltamivir
. Greater reductions in viral load were seen with baloxavir versus placebo or oseltamivir
one day after initiation of the regimen.
THE FOOD AND DRUG ADMINISTRATION has approved the first generic version of Tamiflu (oseltamivir
phosphate), a medication for the treatment of influenza A and B.
, a neuraminidase inhibitor, plays a key role in the management of influenza.
Neuraminidase inhibitors such as oseltamivir
and zanamivir are commonly used for stopping influenza virus infections.
Treatment of influenza virus infection with oral oseltamivir
reduces time to alleviation of symptoms in adults and children by approximately one day compared with placebo.
is the most important and effective drug for severe influenza infections.