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v. os·si·fied, os·si·fy·ing, os·si·fies
1. To change into bone; become bony.
2. To become set in a rigidly conventional pattern: "The central ideas of liberalism have ossified" (Jeffrey Hart).
1. To convert (a membrane or cartilage, for example) into bone.
2. To mold into a rigidly conventional pattern.

[Latin os, oss-, bone; see ost- in Indo-European roots + -fy.]

os·sif′ic (ŏ-sĭf′ĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in classic literature ?
This was what slavery could do, in the way of ossifying what one may call the superior lobe of human feeling; for these pil- grims were kind-hearted people, and they would not have allowed that man to treat a horse like that.
Osteolipomas are extremely rare variants and constitute only 1% of all lipomas; they are alternatively referred to as ossifying lipomas or osseous lipomas [7].
An ossifying renal tumor of infancy (ORTI) is an extremely rare finding, with only 24 published cases in the literature to date [1-3].
Ossifying fibroma (OF) is a rare and benign fibro-osseous neoplasm found most commonly among the bones of the craniomaxillofacial skeleton.
Ossifying fibromyxoid tumor (OFMT) is a rare soft tissue neoplasm first described by Enzinger in 1989 with uncertain differentiation (1).
Psammomatoid juvenile ossifying fibroma (PJOF) and trabecular juvenile ossifying fibroma (TrJOF) are the two histopathological variants reported according to the WHO classification of odontogenic tumours 2005.
An ossifying fibroma is a proliferative, fibro-osseous, tumor-like lesion that develops most commonly in the rostral mandible causing distortion of the lip and adjacent teeth.
Polyps, ossifying fibromas, mucoceles, pyoceles, fungal balls, and cholesteatomas are all extraordinary pathologies that can be found within the cavity of the concha bullosa (11-13).
Histologically, the differential diagnoses of a heavily ossified soft-tissue mass in this particular location may encompass different neoplasms: myositis ossificans, heterotopic ossification (soft-tissue osteomas), ossifying fibromyxoid tumor, or even extraskeletal osteosarcoma.
Ossifying fibromyxoid tumor (OFMT) is a rare musculoskeletal tumor of borderline malignant potential, displaying an uncertain line of differentiation.
(12) When features are not classical, the tumor can mimic ameloblastoma, Pindborg tumor, fibrous dysplasia, ossifying fibroma and even osteosarcoma when the tumor perforates the cortex with the formation of multiple, radiating spicules giving a sunburst appearance.
Ossifying fibroma occurs mostly in craniofacial bones and categorized into two types central and peripheral.