osteocalcin


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os·te·o·cal·cin

 (ŏs′tē-ō-kăl′sĭn)
n.
A calcium-binding substance produced by osteoblasts that is essential to bone mineralization and can be used as a biomarker for osteoporosis. It may also act as a hormone to increase insulin production and insulin sensitivity.
Translations

os·te·o·cal·cin

n. osteocalcina, proteína del hueso.
References in periodicals archive ?
4] CAC involves expression of an altered phenotype of vascular smooth muscle cells (VSMCs) and expression of bone-related proteins such as osteopontin, osteoprotegerin (OPG), osteocalcin, and bone morphogenetic proteins (BMPs).
Osteocalcin is regarded as an important indicator of osteogenesis.
Juarez conducts investigations of osteocalcin and bone density changes in archeological bone as an indicator of diabetes prevalence.
Vitamin K is a bone quality marker which aids to carboxylates osteocalcin to form bone matrix.
Twenty-four hour urine samples were obtained to measure urinary creatinine and calcium levels: blood samples were obtained from the abdominal aorta via an heparinized syringe from which plasma calcium, creatinine, and osteocalcin levels were measured.
Bone metabolism was evaluated by determining serum levels of osteocalcin (OC) as a marker of bone formation, and urinary pyrilinks-D (PYD) and beta-CrossLaps (B-CTx) as markers of bone resorption (18).
We measured both C-telopeptide of type I collagen (CTX-I) and osteocalcin levels via electrochemiluminescence immunoassay method.
Thereafter, the concentrations of osteocalcin, FGF23, PTH, 1,25-(OH)2D3, total calcium, and inorganic phosphorus were measured using the frozen serum samples.
During physical exertion the bones produce a hormone called osteocalcin that increases muscle performance, scientists found.
Osteocalcin and P1NP are two proteins associated with bone formation and their levels in blood are an indicator of bone health.
Clinical and biochemical markers--including disease activity score, erythrocyte sedimentation rate, serum undercarboxylated osteocalcin (a bone metabolism marker that is elevated with low vitamin K status), C- reactive protein, and matrix metalloproteinase, an enzyme that degrades collagens and other tissue components correlated with systemic inflammation of rheumatoid arthritis--were assessed before and after the treatment period.